189120-10-3Relevant articles and documents
Potent benzimidazolone based human β3-adrenergic receptor agonists
Finley, Don R.,Bell, Michael G.,Borel, Anthony G.,Bloomquist, William E.,Cohen, Marlene L.,Heiman, Mark. L.,Kriauciunas, Aidas,Matthews, Donald P.,Miles, Tania,Neel, David A.,Rito, Christopher J.,Sall, Daniel J.,Shuker, Anthony J.,Stephens, Thomas W.,Tinsley, Frank C.,Winter, Mark A.,Jesudason, Cynthia D.
, p. 5691 - 5694 (2007/10/03)
The synthesis and biological evaluation of a series of benzimidazolone β3 adrenergic receptor agonists are described. A trend toward the reduction of rat atrial tachycardia upon increasing steric bulk at the 3-position of the benzimidazolone mo