189252-16-2Relevant articles and documents
A heterogeneous catalytic and solvent-free approach to 1,2-dihydroquinoline derivatives from aromatic amines and alkynes by tandem hydroarylation-hydroamination
Amrutham, Vasu,Agliullin, Marat Radikovich,Mameda, Naresh,Gajula, Krishna Sai,Grigor'eva, Nellya Gennadievna,Kutepov, Boris Ivanovich,Akula, Venugopal,Nama, Narender
, (2020)
This study describes a mesoporous aluminosilicate (ASM) catalyst-induced one-step synthesis of substituted dihydroquinolines through a hydroarylation/hydroamination cascade reaction under solvent-free conditions. A sol-gel method was utilized to prepare t
Palladium-Catalyzed/Copper-Mediated Desulfurization and Aryl- ation of Quinoline-2-(1 H)-thione for Rapid Access to Quinoline Derivatives
Guo, Fu-Hu,Lu, Hai-Long,Quan, Zheng-Jun,Wang, Tong-Lin,Wang, Xi-Cun
supporting information, p. 893 - 900 (2020/03/13)
An efficient method for carbon-carbon bond formation is described. The process employs the palladium-catalyzed and copper-mediated cross-coupling of quinoline-2-(1 H)-thiones with arylboronic acids or alkynes through C-S bond cleavage without an inert atm
Metal-free synthesis of 2-fluoroalkylated quinolines using polyfluoroalkanoic acids as direct fluorine sources
Nan, Jiang,Hu, Yan,Chen, Pu,Ma, Yangmin
supporting information, p. 1984 - 1988 (2019/03/26)
A novel [5 + 1] cyclization of 2-vinylanilines with polyfluoroalkanoic acids under catalyst- A nd additive-free conditions was successfully implemented. The approach directly employs very low-cost and readily available polyfluoroalkanoic acids as both C1 synthons and fluoroalkyl building blocks. This method provides concise access to diverse 2-fluoroalkylated (CF3, C2F5, C3F7, CF2H, CF2Cl, and CF2Br) quinolines in good yields with excellent functional group tolerance in high yield on a gram scale.
