189254-14-6

Basic information

• Product Name: N-Ethyl-4-[6-methoxy-2,3-dihydro-1H-inden-1(R)-yl]piperazine-1-carboxamide
• CAS NO: 189254-14-6
• Molecular Formula: C₁₇H₂₅N₃O₂
• Molecular Weight: 303.4077
• Mol File: 189254-14-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-Ethyl-4-[6-methoxy-2,3-dihydro-1H-inden-1(R)-yl]piperazine-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ethyl-4-[6-methoxy-2,3-dihydro-1H-inden-1(R)-yl]piperazine-1-carboxamide(189254-14-6)
• EPA Substance Registry System: N-Ethyl-4-[6-methoxy-2,3-dihydro-1H-inden-1(R)-yl]piperazine-1-carboxamide(189254-14-6)

Safety Data

• Hazardous Substances Data: 189254-14-6(Hazardous Substances Data)

Upstream product

• 109-90-0 ethyl isocyanate 
• 128226-40-4 1-(piperazin-1-yl)-6-methoxyindan 
• 13623-25-1 6-methoxy-2,3-dihydro-1H-inden-1-one 

Relevant articles and documents

Indanyl piperazines as melatonergic MT2 selective agents

Optimization of a benzyl piperazine pharmacophore produced N-acyl-4-indanyl-piperazines that bind with high affinity to melatonergic MT2 receptors. (R)-4-(2,3-dihydro-6-methoxy-1H-inden-1-yl)-N-ethyl-1-piperazine-carboxamide fumarate (13) is a water soluble, selective MT2 agonist, which produces advances in circadian phase in rats at doses of 1-56 mg/kg that are no different from those of melatonin at 1 mg/kg. Unlike melatonin, 13 produced only weak contractile effects in rat tail artery.