189264-47-9

Basic information

• Product Name: 3,3a,7,7aα-Tetrahydro-3aα-hydroxy-2H-6-benzofuranone
• Synonyms: 3,3a,7,7aα-Tetrahydro-3aα-hydroxy-2H-6-benzofuranone;(+)-Rengyolone;(3aS)-3,3a,7,7aβ-Tetrahydro-3aβ-hydroxybenzofura-6(2H)-one;(3aS)-3aβ-Hydroxy-2,3,3a,7aβ-tetrahydrobenzofuran-6(7H)-one;(3aS,7aS)-3,3a,7,7a-Tetrahydro-3a-hydroxy-2H-6-benzofuranone;Cleroindicin F;(3aR,7aR)-3,3a,7,7a-Tetrahydro-3a-hydroxy-6(2H)-benzofuranone;ent-Cleroindicin F
• CAS NO: 189264-47-9
• Molecular Formula: C8H10O3
• Molecular Weight: 154.1632
• Mol File: 189264-47-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 307.5 °C at 760 mmHg
• Flash Point: 139.771 °C
• Appearance: /
• Density: 1.202 g/cm³
• PKA: 12.88±0.20(Predicted)
• CAS DataBase Reference: 3,3a,7,7aα-Tetrahydro-3aα-hydroxy-2H-6-benzofuranone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3a,7,7aα-Tetrahydro-3aα-hydroxy-2H-6-benzofuranone(189264-47-9)
• EPA Substance Registry System: 3,3a,7,7aα-Tetrahydro-3aα-hydroxy-2H-6-benzofuranone(189264-47-9)

Safety Data

• Hazardous Substances Data: 189264-47-9(Hazardous Substances Data)

Usage

General Description

3,3a,7,7aα-Tetrahydro-3aα-hydroxy-2H-6-benzofuranone, also known as dihydrocoumarin, is a synthetic chemical compound commonly used in the food and fragrance industries. It has a sweet, vanilla-like scent and is often added to perfumes, lotions, and air fresheners to impart a warm, sweet aroma. In addition to its use in the fragrance industry, dihydrocoumarin is also utilized as a flavoring agent in various food products, particularly in baked goods and desserts. However,

Upstream product

• 443095-50-9 ethyl 2-[(2R,3R)-8-hydroxy-2,3-diphenyl-1,4-dioxaspiro[4.5]deca-6,9-dien-8-yl]acetate 
• 443923-77-1 (2R,3R)-8-(2-hydroxy)ethyl-2,3-diphenyl-1,4-dioxaspiro[4.5]deca-6,9-dien-8-ol 
• 189264-45-7 cleroindicin D 

Downstream Products

• 189264-44-6 cleroindicin C 

Relevant articles and documents

Catalytic enantioselective silylation of acyclic and cyclic triols: Application to total syntheses of cleroindicins D, F, and C

(Chemical Equation Presented) Pick one out of three: Acyclic and cyclic 1,2,3-triols are silylated with exceptional site- and enantioselectivity by a small-molecule catalyst to afford silyl ethers having a neighboring diol moiety. The new process is appli

First synthesis of (+)-rengyolone and (+)- and (-)-menisdaurilide

The benzofuranone natural products (+)-rengyolone and (+)- and (-)-menisdaurilide have been synthesised for the first time from a common enantiopure cyclohexane building block derived from a monoketal of p-benzoquinone.