18982-18-8Relevant articles and documents
METHOD FOR MANUFACTURING P-HYDROXY BENZOIC ACID ALLYL POLYMER
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Paragraph 0049, (2017/02/24)
PROBLEM TO BE SOLVED: To provide a method for efficiently manufacturing p-hydroxy benzoic acid allyl polymer having high antibacterial property. SOLUTION: There is provided a method for manufacturing p-hydroxy benzoic acid allyl polymer including (A) a pr
A simple FRET-based modular design for diagnostic probes
Redy, Orit,Kisin-Finfer, Einat,Sella, Eran,Shabat, Doron
supporting information; scheme or table, p. 710 - 715 (2012/02/05)
In recent years, there has been a massive effort to develop molecular probes with optical modes of action. Probes generally produce detectable signals based on changes in fluorescence properties. Here, we demonstrate the potential of self-immolative molecular adaptors as a platform for Turn-On probes based on the FRET technique. The probe is equipped with identical fluorophore pairs or a fluorophore/quencher FRET pair and a triggering substrate. Upon reaction of the analyte of interest with the triggering substrate, the self-immolative adaptor spontaneously releases the two dye molecules to break off the FRET effect. As a result, a new measurable fluorescent signal is generated. The fluorescence obtained can be used to quantify the analyte. The modular structure of the probe design will allow the preparation of various chemical probes based on the FRET activation technique.
Synthesis of para-substituted bicyclo[2.2.1]hept-5-en-2-ylmethyl benzoates
Mamedbeili,Kyazimova,Nagiev,Abdiev,Aliev
experimental part, p. 74 - 77 (2009/07/17)
para-Substituted bicyclo[2.2.1]hept-5-en-2-ylmethyl benzoates were synthesized by the Diels-Alder reaction of cyclopentadiene with the corresponding para-substituted allyl benzoates, and optimal reaction conditions were found. The product structure was confirmed by independent synthesis and IR and 1H NMR spectroscopy.