189950-17-2

Basic information

• Product Name: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester, (1R,2S,3S,5S)-
• CAS NO: 189950-17-2
• Molecular Formula: C15H18BrNO2
• Molecular Weight: 324.217
• Mol File: 189950-17-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester, (1R,2S,3S,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester, (1R,2S,3S,5S)-(189950-17-2)
• EPA Substance Registry System: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester, (1R,2S,3S,5S)-(189950-17-2)

Safety Data

• Hazardous Substances Data: 189950-17-2(Hazardous Substances Data)

Upstream product

• 50373-10-9 methyl ecgonidine 
• 17878-43-2 [4-(trimethylsilyl)phenyl]magnesium bromide 
• 174224-35-2 2β-carbomethoxy-3β-(4'-trimethylsilylphenyl)tropane 
• 135367-08-7 RTI 51 
• 303733-94-0 N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4-bromophenyl)nortropane 
• 18620-02-5 (4-bromophenyl)magnesium bromide 

Downstream Products

• 869845-23-8 2β-carbomethoxy-3β-(4'-(3-furyl)phenyl)nortropane 
• 910252-40-3 (1R,2S,3S,5S)-3-(4-Bromo-phenyl)-8-ethoxycarbonylmethyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester 
• 1236307-81-5 C₁₉H₂₃Br⁽¹⁸⁾FNO₂ 
• 869845-29-4 N-(tert-butoxycarbonyl)-3β-(4'-(3-furyl)phenyl)nortropane-2β-carboxylic acid 
• 869845-28-3 3β-(4'-(3-furyl)phenyl)nortropane-2β-carboxylic acid 
• 910252-42-5 (1S,3S,4R,8R)-3-(4-Bromo-phenyl)-5-methylene-7-aza-tricyclo[5.3.0.0^4,8]decane 
• 910252-41-4 (1S,3S,4S,8R)-3-(4-Bromo-phenyl)-7-aza-tricyclo[5.3.0.0^4,8]decan-5-one 
• 674283-49-9 2β-carbomethoxy-3β-[4'-((Z)-2-bromoethenyl)phenyl]nortropane 

Relevant articles and documents

Synthesis and monoamine transporter affinity of front bridged tricyclic 3β-(4′-halo or 4′-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2β-position

A series of front bridged tricyclic 3β-(4′-halo or 4′-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2β-position was synthesized, and their binding affinities were determined in cells transfected to express human nor

Synthesis and biological evaluation of a series of novel N- or O-fluoroalkyl derivatives of tropane: Potential positron emission tomography (PET) imaging agents for the dopamine transporter

A series of novel fluoroalkyl-containing tropane derivatives was synthesized, and their binding affinities for the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET) were determined via competitive binding assays. Among these derivatives, the fluoropropyl ester of β-CIT (19), the fluoroethyl ester of β-CIT (20), the N-fluoropropyl derivative of β-CBT (12), and the fluoropropyl ester of β-CMT (18) displayed higher affinity and greater selectivity for the DAT versus SERT and NET than FP-CIT, which indicates that they are attractive candidates for the development of 18F-labeled PET imaging agents for the DAT.