19005-60-8

Basic information

• Product Name: 1H-Pyrazole, 3,5-dimethyl-1-(pentafluorophenyl)-
• CAS NO: 19005-60-8
• Molecular Formula: C11H7F5N2
• Molecular Weight: 262.182
• Mol File: 19005-60-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole, 3,5-dimethyl-1-(pentafluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole, 3,5-dimethyl-1-(pentafluorophenyl)-(19005-60-8)
• EPA Substance Registry System: 1H-Pyrazole, 3,5-dimethyl-1-(pentafluorophenyl)-(19005-60-8)

Safety Data

• Hazardous Substances Data: 19005-60-8(Hazardous Substances Data)

Usage

Chemical Family

1H-Pyrazole

Molecular Structure

Pyrazole ring with two methyl groups at positions 3 and 5, and a pentafluorophenyl group attached at position 1

Usage

Building block for the synthesis of various pharmaceutical compounds, studied for potential biological and pharmacological activities, including antimicrobial and antifungal properties, used in the formulation of agrochemicals and crop protection products.

Upstream product

• 123-54-6 acetylacetone 
• 828-73-9 pentafluorophenyl hydrazine 

Relevant articles and documents

Reaction of 2-azidobenzothiazole and 1-azido-4-(3',5'-dimethyl-1'-pyrazolyl)tetrafluorobenzene with [60]fullerene and characterization of the adducts by fast-atom bombardment mass spectrometry

By FAB-MS and 13C NMR spectroscopy the structures of three new imino[60]fullerenes have been established: two monoadducts 5 (σ-azaridinefullerene) and 7 (π-azafullaroid) and one bisadduct (π-bisazafullaroid) 8.

REACTION OF DIAZOLE ANIONS WITH HEXAFLUOROBENZENE: AN UNEXPECTEDLY FACILE ENTRY INTO HEXA(DIAZOL-1-YL)-BENZENES

Diazole anions react with hexafluorobenzene to give hexa(diazol-1-yl)benzenes in excellent yield, even with unfavorable reaction stoichiometries.In contrast, pyrrole anions predominantly or exclusively 1,4-disubstituted products.This novel hexasubstitution reaction is discussed in terms of an SRN1 mechanism.