19031-66-4

Basic information

• Product Name: Benzene, (3-fluoro-3-methylbutyl)-
• CAS NO: 19031-66-4
• Molecular Formula: C11H15F
• Molecular Weight: 166.239
• Mol File: 19031-66-4.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzene, (3-fluoro-3-methylbutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (3-fluoro-3-methylbutyl)-(19031-66-4)
• EPA Substance Registry System: Benzene, (3-fluoro-3-methylbutyl)-(19031-66-4)

Safety Data

• Hazardous Substances Data: 19031-66-4(Hazardous Substances Data)

Upstream product

• 2550-26-7 4-Phenyl-2-butanone 
• 917-54-4 methyllithium 
• 103-05-9 4-phenyl-2-methyl-2-butanol 
• 6683-51-8 2-methyl-4-phenyl-1-butene 
• 52017-21-7 (3-bromo-3-methyl-n-butyl)benzene 
• 1361152-14-8 tert-butyl 2,2-dimethyl-4-phenylbutaneperoxoate 

Downstream Products

• 4830-95-9 2-chloro-2-methyl-4-phenylbutane 
• 17314-92-0 (3,3-dimethylbutyl)benzene 
• 52356-07-7 3.3-Dimethyl-1-phenyl-pentan 
• 32366-28-2 (3-azido-3-methyl-butyl)-benzene 
• 79399-21-6 (2-methyl-4-phenylbutan-2-yl)(phenyl)sulfane 

Relevant articles and documents

Dehydroxylative Fluorination of Tertiary Alcohols

A large number of fluorination methods have been developed, but the construction of a tertiary C-F bond remains challenging. Herein, we describe an efficient dehydroxylative fluorination of tertiary alcohols with Selectfluor via the activation of a hydroxyl group by a Ph2PCH2CH2PPh2/ICH2CH2I system. Although the reagents appear to be not compatible (Selectfluor with the phosphine and I- generated in situ), the reactions occur rapidly to give the desired products in moderate to high yields. This work may present a new discovery in fluorination of alcohols since the reported methods are mainly limited to primary and secondary alcohols.

Predictable site-selective radical fluorination of tertiary ethers

In this communication, we disclose the first example of metal-free and site-selective radical fluorination of readily available tertiary alkyl ethers, enabled by synergistic photocatalysis and organocatalysis. This catalytic combination allows for exclusi

Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor

Herein we disclose a deoxyfluorination of alcohols with an electrophilic fluorine source via visible-light photoredox catalysis. This radical-mediated C–F coupling is capable of fluorinating secondary and tertiary alcohols efficiently, complementing previously reported nucleophilic deoxyfluorination protocols.