190367-38-5

Basic information

• Product Name: 4-fluoro-2-methyl-5-(methylsulfonyl)benzoic acid
• Synonyms: 4-fluoro-2-methyl-5-(methylsulfonyl)benzoic acid
• CAS NO: 190367-38-5
• Molecular Weight: 232.232
• Mol File: 190367-38-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-fluoro-2-methyl-5-(methylsulfonyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-fluoro-2-methyl-5-(methylsulfonyl)benzoic acid(190367-38-5)
• EPA Substance Registry System: 4-fluoro-2-methyl-5-(methylsulfonyl)benzoic acid(190367-38-5)

Safety Data

• Hazardous Substances Data: 190367-38-5(Hazardous Substances Data)

Upstream product

• 74-11-3 para-chlorobenzoic acid 
• 1026030-54-5 5-(chlorosulfonyl)-4-fluoro-2-methylbenzoic acid 
• 1027944-24-6 4-Fluoro-2-methyl-5-sulfino-benzoic acid 
• 321-21-1 4-fluoro-2-methylbenzoic acid 
• 7499-07-2 4-chloro-2-methylbenzoic acid 
• 452-63-1 2-Bromo-5-fluorotoluene 
• 201230-82-2 carbon monoxide 
• 294204-21-0 1-bromo-4-fluoro-2-methyl-5-(methylsulfonyl)benzene 
• 190367-50-1 4-fluoro-5-methanesulfonyl-2-methyl-benzoic acid methyl ester 

Downstream Products

• 190367-76-1 5-Methanesulfonyl-2-methyl-4-propylsulfanyl-benzoic acid 
• 190368-19-5 5-Methanesulfonyl-2-methyl-4-phenylamino-benzoic acid 
• 190368-20-8 4-(3-Chloro-phenylamino)-5-methanesulfonyl-2-methyl-benzoic acid 
• 1026482-41-6 4-Fluoro-5-methanesulfonyl-2-methyl-benzoyl chloride 
• 177970-06-8 4-tert-Butoxy-5-methanesulfonyl-2-methyl-benzoic acid methyl ester 
• 1027515-32-7 5-Methanesulfonyl-2-methyl-4-propylsulfanyl-benzoyl chloride 
• 176309-15-2 N-diaminomethylene-2-methyl-4-fluoro-5-methylsulphonylbenzamide 
• 180867-07-6 5-Methanesulfonyl-2-methyl-4-phenylamino-benzoyl chloride 
• 180867-08-7 4-(3-Chloro-phenylamino)-5-methanesulfonyl-2-methyl-benzoyl chloride 
• 190368-22-0 5-Methanesulfonyl-2-methyl-4-(pyrimidin-2-ylamino)-benzoic acid methyl ester 
• 294204-23-2 1-(benzyloxycarbonyl)-3-[2-methyl-5-methylsulfonyl-4-(pyrrol-1-yl)-benzoyl]guanidine 
• 294204-22-1 2-methyl-5-methylsulfonyl-4-(pyrrol-1-yl)benzoic acid 
• 190367-77-2 4-tert-Butylsulfanyl-5-methanesulfonyl-2-methyl-benzoic acid 
• 1027937-98-9 5-Methanesulfonyl-2-methyl-4-(pyrimidin-2-ylamino)-benzoic acid 

Relevant articles and documents

A concise and efficient synthesis of [2-methyl-5-methylsulfonyl-4- (pyrrol-1-yl)benzoyl]guanidinium methanesulfonate (Eniporide)

A new synthesis of the benzoylguanidine-type Na+/H+ antiporter inhibitor eniporide (7) is described. Starting from 2-bromo-5-fluorotoluene (1), aromatic substituents were introduced by methanesulfonylation, Pd- catalyzed carboxylation with CO, and halogen-pyrrole exchange. Guanidine acylation was performed using Mukaiyama's procedure.