190383-61-0

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 2-[(2R)-oxiranylmethyl]-, phenylmethyl ester, (2S)-
• CAS NO: 190383-61-0
• Molecular Formula: C16H21NO3
• Molecular Weight: 275.348
• Mol File: 190383-61-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 2-[(2R)-oxiranylmethyl]-, phenylmethyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 2-[(2R)-oxiranylmethyl]-, phenylmethyl ester, (2S)-(190383-61-0)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 2-[(2R)-oxiranylmethyl]-, phenylmethyl ester, (2S)-(190383-61-0)

Safety Data

• Hazardous Substances Data: 190383-61-0(Hazardous Substances Data)

Upstream product

• 190383-56-3 [2S-(2R)]-1-benzyloxycarbonyl-2-(2,3-dihydroxypropyl)piperidine 
• 184535-16-8 (S)-1-benzyloxycarbonyl-2-(2-propenyl)piperidine 
• 1445-45-0 Trimethyl orthoacetate 
• 506-96-7 Acetyl bromide 

Downstream Products

• 251995-54-7 [2R-(2R)]-phenylmethyl 2-(2-(2,5-dioxopyrrolidinyl)heptyl)piperidinecarboxylate 
• 251995-64-9 (-)-benzyl (S)-2-[(S)-2-hydroxypropyl]piperidine-1-carboxylate 
• 190383-64-3 benzyl (2S)-2-[(2S)-2-hydroxybutyl]piperidine-1-carboxylate 
• 251995-52-5 [2R-(2S)]-phenylmethyl 2-(2-hydroxyheptyl)piperidinecarboxylate 

Relevant articles and documents

A general entry to 2-(2-hydroxyalkyl)piperidines via iterative asymmetric dihydroxylation to cause enantiomeric enhancement

Both enantiomers of 2-(2-propenyl)piperidine (1) (76-88% ee), prepared via the first AD of 5-hexenyl azide, underwent the second AD to provide all of the four stereoisomeric 2-(2-hydroxypropyl)piperidines (2) with enantiomeric enhancement (>98 ee). An asy