190433-54-6

Basic information

• Product Name: Benzeneacetamide, 3-chloro-a-oxo-N-(phenylmethyl)-
• CAS NO: 190433-54-6
• Molecular Formula: C15H12ClNO2
• Molecular Weight: 273.719
• Mol File: 190433-54-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetamide, 3-chloro-a-oxo-N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetamide, 3-chloro-a-oxo-N-(phenylmethyl)-(190433-54-6)
• EPA Substance Registry System: Benzeneacetamide, 3-chloro-a-oxo-N-(phenylmethyl)-(190433-54-6)

Safety Data

• Hazardous Substances Data: 190433-54-6(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 62123-73-3 ethyl 2‐(3‐chlorophenyl)‐2‐oxoacetate 
• 36229-42-2 (3-chlorophenyl)magnesium bromide 
• 34966-50-2 methyl 2-(3-chlorophenyl)-2-oxoacetate 
• 26767-07-7 2-(3-chlorophenyl)-2-oxoacetic acid 
• 625-99-0 3-iodochlorobenzene 
• 21667-62-9 3-chlorobenzoylacetonitrile 

Relevant articles and documents

Synthesis of α-Ketoamides from β-Ketonitriles and Primary Amines: A Catalyst-Free Oxidative Decyanation–Amidation Reaction

AN oxidative decyanation–amidation of β-ketonitriles and primary amines readily occurs using hydrogen peroxide sodium carbonate adduct (Na2CO3·1.5H2O2), K2CO3, and 1,4-dioxane. This reactio

Enantioselective Iridium-Catalyzed Hydrogenation of α-Keto Amides to α-Hydroxy Amides

A highly enantioselective iridium-catalyzed hydrogenation of α-keto amides to form α-hydroxy amides has been achieved with excellent results (up to >99% conversion and up to >99% ee, TON up to 100?000). As an example, this protocol was applied to the synthesis of (S)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol, the enantiomer of norepinephrine, which is widely used as an injectable drug for the treatment of critically low blood pressure. Density functional theory (DFT) calculations were also carried out to reveal the reaction mechanism.