190451-39-9

Basic information

• Product Name: (1R,2S,4aR,8aR)-2-hydroxy-decahydro-5,5,8a-trimethyl-1-naphthylmethanol
• Synonyms: (1R,2S,4aR,8aR)-2-hydroxy-decahydro-5,5,8a-trimethyl-1-naphthylmethanol
• CAS NO: 190451-39-9
• Molecular Weight: 226.359
• Mol File: 190451-39-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,2S,4aR,8aR)-2-hydroxy-decahydro-5,5,8a-trimethyl-1-naphthylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,4aR,8aR)-2-hydroxy-decahydro-5,5,8a-trimethyl-1-naphthylmethanol(190451-39-9)
• EPA Substance Registry System: (1R,2S,4aR,8aR)-2-hydroxy-decahydro-5,5,8a-trimethyl-1-naphthylmethanol(190451-39-9)

Safety Data

• Hazardous Substances Data: 190451-39-9(Hazardous Substances Data)

Upstream product

• 65754-92-9 (+/-)-methyl (1β,2α,4aα,8aβ)-2-formyloxy-decahydro-5,5,8a-trimethylnaphthalene-1-carboxylate 
• 59633-91-9 rac-12-nor-drimane-8α,11-diol 

Downstream Products

• 211053-91-7 (4aR,5S,6S,8aR)-6-Benzyloxy-5-bromomethyl-1,1,4a-trimethyl-decahydro-naphthalene 
• 211053-87-1 ((1R,2S,4aR,8aR)-2-Benzyloxy-5,5,8a-trimethyl-decahydro-naphthalen-1-yl)-methanol 
• 211053-83-7 (-)-(4aR,8aR)-1-(2,5-dimethoxyphenyl)methyl-2-acetoxy-3,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethylnaphthalene 
• 69880-60-0 (+)-zonarol dimethyl ether 
• 108944-90-7 (1S,4aR,8aR)-(+)-1-(2,5-dimethoxyphenyl)methyl-2-oxo-5,5,8a-trimethyldecahydronaphthalene 
• 211053-86-0 (3R,4aS,6aR,10aR,10bR)-7,7,10a-Trimethyl-3-phenyl-decahydro-naphtho[2,1-d][1,3]dioxine 

Relevant articles and documents

Simple approach to optically active drimane sesquiterpenes based on enzymatic resolution

When the β-acyloxy esters (±)-10 and (±)-II were exposed to the lipase OF-360 from Candida rugosa or immobilized lipase OF-360 in a water- saturated organic solvent, the hydrolyzed product (8aS)-6 was obtained in high chemical (40%) and optical (>99%ee) yields. The absolute structure of (8aS)-6 was confirmed by the fact that (8aS)-6 was converted into an authentic sample γ-keto nitrile (8aS)-17. Treatment of the diol (±)-12 with isopropenyl acetate in the presence of the lipase Godo E-4 from Pseudomonas sp. provided the unchanged (8aR)-12 (89% ee) in 42% yield.