19064-18-7 Usage
Description
2,6-Difluorobenzyl alcohol is an organic compound characterized by the presence of two fluorine atoms at the 2nd and 6th positions of a benzyl alcohol molecule. It is a clear colorless to light yellow liquid with unique chemical properties that make it suitable for various applications in different industries.
Uses
Used in Chemical Synthesis:
2,6-Difluorobenzyl alcohol is used as a chemical intermediate for the synthesis of various organic compounds, including 2-(bromomethyl)-1,3-difluorobenzene. Its unique fluorinated structure allows for the creation of a range of specialized chemicals with specific properties and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,6-Difluorobenzyl alcohol can be used as a building block for the development of new drugs with potential therapeutic applications. Its fluorinated structure may contribute to enhanced bioavailability, metabolic stability, and target specificity, which are crucial factors in drug design.
Used in Material Science:
2,6-Difluorobenzyl alcohol may also find applications in the field of material science, where its fluorinated nature could be exploited to develop new materials with improved properties, such as increased hydrophobicity, chemical resistance, or thermal stability.
Used in Agrochemicals:
In the agrochemical industry, 2,6-Difluorobenzyl alcohol could be utilized as a starting material for the synthesis of novel pesticides or herbicides with enhanced efficacy and selectivity, thanks to its unique fluorinated structure.
Overall, 2,6-Difluorobenzyl alcohol is a versatile compound with a wide range of potential applications across various industries, including chemical synthesis, pharmaceuticals, material science, and agrochemicals. Its unique chemical properties and fluorinated structure make it a valuable asset in the development of new and improved products.
Check Digit Verification of cas no
The CAS Registry Mumber 19064-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,6 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19064-18:
(7*1)+(6*9)+(5*0)+(4*6)+(3*4)+(2*1)+(1*8)=107
107 % 10 = 7
So 19064-18-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H11BrO3/c6-1-5(2-7,3-8)4-9/h7-9H,1-4H2
19064-18-7Relevant articles and documents
Preparation method of 2, 6-difluorobenzyl alcohol
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Paragraph 0027-0069, (2021/11/10)
The invention discloses a preparation method of 2, 6-difluorobenzyl alcohol. By adding a phase transfer catalyst, a reduction reaction can be carried out in two phases, and the yield of the reduction reaction can be obviously improved. Part of NaBH4 is dissolved in advance, and the rest NaBH4 is added in batches subsequently, so that the reduction efficiency of the NaBH4 is improved, and the purpose of improving the yield of the reduction reaction is finally achieved. By adding a Lewis acid catalyst, the reduction reaction yield can be effectively improved, the purity of 2, 6-difluorobenzyl alcohol is improved, and the residual amount of methyl 2, 6-difluorobenzoate is reduced.
Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency
Bollini, Mariela,Gallardo-Macias, Ricardo,Spasov, Krasimir A.,Tirado-Rives, Julian,Anderson, Karen S.,Jorgensen, William L.
, p. 1110 - 1113 (2013/03/14)
Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved activity towards Tyr181Cys containing variants was pursued with the assistance of free energy perturbation (FEP) calculations. Optimization of the 4-R substituent in 1 led to ethyl and isopropyl analogs 1e and 1f with 1-7 nM potency towards both the wild-type virus and a Tyr181C variant.
