190838-91-6

Basic information

• Product Name: (3aR,6S,6aR)-6-Isopropyl-3,3-dimethyl-5-(toluene-4-sulfonyl)-hexahydro-pyrrolo[3,4-c]isoxazole
• Synonyms: (3aR,6S,6aR)-6-Isopropyl-3,3-dimethyl-5-(toluene-4-sulfonyl)-hexahydro-pyrrolo[3,4-c]isoxazole
• CAS NO: 190838-91-6
• Molecular Weight: 338.471
• Mol File: 190838-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3aR,6S,6aR)-6-Isopropyl-3,3-dimethyl-5-(toluene-4-sulfonyl)-hexahydro-pyrrolo[3,4-c]isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,6S,6aR)-6-Isopropyl-3,3-dimethyl-5-(toluene-4-sulfonyl)-hexahydro-pyrrolo[3,4-c]isoxazole(190838-91-6)
• EPA Substance Registry System: (3aR,6S,6aR)-6-Isopropyl-3,3-dimethyl-5-(toluene-4-sulfonyl)-hexahydro-pyrrolo[3,4-c]isoxazole(190838-91-6)

Safety Data

• Hazardous Substances Data: 190838-91-6(Hazardous Substances Data)

Upstream product

• 190838-88-1 N-((S)-1-Hydroxymethyl-2-methyl-propyl)-4-methyl-N-(3-methyl-but-2-enyl)-benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 139192-48-6 (S)-N-(1-hydroxy-3-methylbutan-2-yl)-4-methylbenzenesulfonamide 
• 2026-48-4 (S)-valinol 
• 196935-48-5 N-[(S)-1-(Hydroxyimino-methyl)-2-methyl-propyl]-4-methyl-N-(3-methyl-but-2-enyl)-benzenesulfonamide 

Downstream Products

• 190838-95-0 1-[(3aR,6S,6aR)-6-Isopropyl-3,3-dimethyl-5-(toluene-4-sulfonyl)-hexahydro-pyrrolo[3,4-c]isoxazol-1-yl]-propan-1-one 

Relevant articles and documents

New isoxazolidine-based chiral auxiliaries for asymmetric syntheses

New chiral auxiliaries based on the bicyclic-isoxazolidine skeleton, 3-oxa-2,7-diazabicylo[3,3,0]octane derivatives, were synthesized in 60-80% overall yields from amino acids. Asymmetric alkylation and boron aldol reaction using the auxiliaries proceeded with high selectivities. 'Carboxylic amide' has been used for the asymmetric boron-mediated aldol reaction for the first time.