190850-76-1

Basic information

• Product Name: (2S,3S)-1,4-Dichlorobutane-diol Sulfate
• Synonyms: (2S,3S)-1,4-Dichlorobutane-diol Sulfate;(4S,5S)-4,5-Bis(chloromethyl)-1,3,2-dioxathiolane 2,2-dioxide;(4S-trans)-4,5-Bis(chloromethyl)-1,3,2-dioxathiolane 2,2-dioxide
• CAS NO: 190850-76-1
• Molecular Formula: C4H6Cl2O4S
• Molecular Weight: 221.06
• Product Categories: Chiral Reagents;Sulfur & Selenium Compounds;Chiral Reagents, Sulfur & Selenium Compounds
• Mol File: 190850-76-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 356.603°C at 760 mmHg
• Flash Point: 169.468°C
• Appearance: /
• Density: 1.554g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.48
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: (2S,3S)-1,4-Dichlorobutane-diol Sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-1,4-Dichlorobutane-diol Sulfate(190850-76-1)
• EPA Substance Registry System: (2S,3S)-1,4-Dichlorobutane-diol Sulfate(190850-76-1)

Safety Data

• Hazardous Substances Data: 190850-76-1(Hazardous Substances Data)

Usage

Description

(2S,3S)-1,4-Dichlorobutane-diol Sulfate, with the CAS number 190850-76-1, is an off-white solid compound that is primarily utilized in the field of organic synthesis. It is a chiral molecule with two stereocenters, which makes it a valuable building block for the creation of various complex organic molecules.

Uses

Used in Organic Synthesis:
(2S,3S)-1,4-Dichlorobutane-diol Sulfate is used as a synthetic building block for the creation of complex organic molecules. Its unique stereochemistry and functional groups make it a versatile starting material for the synthesis of a wide range of compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2S,3S)-1,4-Dichlorobutane-diol Sulfate is used as a key intermediate in the synthesis of various chiral drugs. Its specific stereochemistry allows for the selective formation of desired enantiomers, which is crucial for the development of effective and safe medications.
Used in Agrochemical Industry:
(2S,3S)-1,4-Dichlorobutane-diol Sulfate is also employed in the agrochemical industry for the synthesis of chiral pesticides and other agrochemical products. Its unique properties enable the development of more targeted and environmentally friendly solutions for pest control and crop protection.
Used in Specialty Chemicals:
In the specialty chemicals sector, (2S,3S)-1,4-Dichlorobutane-diol Sulfate is used as a starting material for the synthesis of various chiral compounds with specific applications, such as chiral catalysts, chiral ligands, and chiral auxiliaries. These compounds play a vital role in the development of new materials and technologies with improved performance and selectivity.

InChI:InChI=1/C4H6Cl2O4S/c5-1-3-4(2-6)10-11(7,8)9-3/h3-4H,1-2H2/t3-,4-/m1/s1

Upstream product

• 139165-54-1 (2S,3S)-1,4-dichlorobutan-2,3-diol 

Relevant articles and documents

Synthesis of a chiral aziridine derivative as a versatile intermediate for HIV protease inhibitors.

[reaction: see text] Chiral aziridine derivative 1 was prepared from D-tartaric acid. This compound could be utilized as a common intermediate for the synthesis of hydroxyethylamine class HIV protease inhibitors such as saquinavir, amprenavir, or nelfinavir.

Catalytic asymmetric synthesis of new halogenated chiral synthons

Two-step and practical asymmetric syntheses of enantiomerically pure 4-trifluoromethyl-2.2-dioxo-1,3,2-dioxathiolane and 4-trichloromethyl-2,2-dioxo-1,3,2-dioxathiolane (>98% ee) have been achieved. Catalytic asymmetric dihydroxylation (AD) of 3,3,3-trifl