191030-85-0

Basic information

• Product Name: 5-(4-chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid
• CAS NO: 191030-85-0
• Molecular Weight: 298.729
• Mol File: 191030-85-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid(191030-85-0)
• EPA Substance Registry System: 5-(4-chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid(191030-85-0)

Safety Data

• Hazardous Substances Data: 191030-85-0(Hazardous Substances Data)

Upstream product

• 26377-17-3 ethyl 3-oxo-3-(4-pyridyl)propanoate 
• 191030-84-9 5-(4-chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 536-38-9 4-chlorobenzoylmethyl bromide 

Relevant articles and documents

Potent, orally absorbed glucagon receptor antagonists

The SAR of 2-pyridyl-3,5-diaryl pyrroles, ligands of the human glucagon receptor and inhibitors of p38 kinase, were investigated. This effort resulted in the identification of 2-(4-pyridyl)-5-(4-chlorophenyl)-3-(5- bromo-2-propyloxyphenyl)pyrrole 49 (L-168,049), a potent (Kb = 25 nM), selective antagonist of glucagon.