191104-42-4

Basic information

• Product Name: L-2-methyl-4-N-benzoylpentaphenone
• Synonyms: L-2-methyl-4-N-benzoylpentaphenone
• CAS NO: 191104-42-4
• Molecular Weight: 295.381
• Mol File: 191104-42-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-2-methyl-4-N-benzoylpentaphenone(CAS DataBase Reference)
• NIST Chemistry Reference: L-2-methyl-4-N-benzoylpentaphenone(191104-42-4)
• EPA Substance Registry System: L-2-methyl-4-N-benzoylpentaphenone(191104-42-4)

Safety Data

• Hazardous Substances Data: 191104-42-4(Hazardous Substances Data)

Upstream product

• 1466-83-7 N-benzoyl-L-leucine 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 5468-37-1 2-aminoacetophenone hydrochloride 

Relevant articles and documents

Pyrrolomorphinans as δ opioid receptor antagonists. The role of steric hindrance in conferring selectivity

A series of 2',3'-disubstituted pyrrolomorphinans (5a-i) were synthesized to determine the role of steric hindrance at μ and γ receptors in promoting δ opioid receptor antagonist selectivity. In smooth muscle preparations, five members of the series (5a-c,e,f) possessed K(e) values in the range 2-15 nM and were 6 selective. Since the unsubstituted analogue 4 possessed δ antagonist potency of similar magnitude, but was not δ selective, it is suggested that the 2',3'substitution confers δ selectivity by hindering the interaction of the pharmacophore at μ and γ receptors, while not affecting δ receptors.