191348-16-0 Usage
Description
FMOC-TYR(PO(OBZL)OH)-OH, also known as N-Fmoc-O-benzylphospho-L-tyrosine, is a chemical compound that serves as a pharmaceutical intermediate. It is a white to off-white powder in appearance and is utilized in the synthesis of various pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
FMOC-TYR(PO(OBZL)OH)-OH is used as a pharmaceutical intermediate for the synthesis of various drugs. Its role in the industry is crucial as it aids in the development of new medications and therapies.
As a pharmaceutical intermediate, FMOC-TYR(PO(OBZL)OH)-OH is used for the following reasons:
1. It serves as a building block in the synthesis of complex drug molecules, allowing for the creation of a wide range of pharmaceuticals with diverse therapeutic applications.
2. Its chemical properties, such as being a white to off-white powder, make it suitable for use in the pharmaceutical industry, where purity and stability are essential.
3. The compound's versatility in chemical reactions enables the development of innovative drug candidates with improved efficacy, safety, and pharmacokinetic profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 191348-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,3,4 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 191348-16:
(8*1)+(7*9)+(6*1)+(5*3)+(4*4)+(3*8)+(2*1)+(1*6)=140
140 % 10 = 0
So 191348-16-0 is a valid CAS Registry Number.
InChI:InChI=1/C31H28NO8P/c33-30(34)29(18-21-14-16-23(17-15-21)40-41(36,37)39-19-22-8-2-1-3-9-22)32-31(35)38-20-28-26-12-6-4-10-24(26)25-11-5-7-13-27(25)28/h1-17,28-29H,18-20H2,(H,32,35)(H,33,34)(H,36,37)/t29-/m0/s1
191348-16-0Relevant articles and documents
PROCESS FOR PREPARING PHOSPHORYLATED AMINO ACIDS
-
Page/Page column 70-71; 75; 78, (2013/03/26)
The present invention provides a short, safe, inexpensive, commercially scalable process for preparing a phosphorylated amino acid of Formula I, which can be performed in one pot without isolating any synthetic intermediates.
A general preparation of protected phosphoamino acids
Petrillo, Daniel E.,Mowrey, Dale R.,Allwein, Shawn P.,Bakale, Roger P.
, p. 1206 - 1209 (2012/05/04)
Fmoc-O-benzyl-l-phosphoserine is an important building block in the synthesis of Forigerimod, a phosphopeptide being investigated for Systemic Lupus Erythematosus (SLE). An efficient one-pot process was developed using inexpensive, readily available starting materials. This general procedure was used to prepare a variety of protected phosphoamino acids.