191402-57-0Relevant articles and documents
Efficiency synthesis of compounds with trifluoromethyl benzyl halide structure catalyzed by nickel salt and conversion application thereof
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Paragraph 0176-0184, (2020/01/25)
The invention discloses efficiency synthesis of compounds with trifluoromethyl benzyl halide structure catalyzed by a nickel salt and conversion application thereof. The method is to synthesize the compound of formula C from the compound of formula A1 or A2 and the compound of formula B under the catalysis of the nickel salt and in the presence of a basic compound and/or ligand. The definition ofthe compound is shown in the specification. The method has the advantages of simple and easily available raw materials, less catalyst dosage, wide substrate application range, simple operation, high reaction efficiency and the like, and the prepared product can be further converted into various important trifluoromethyl-containing compounds which are widely applied in aspects of biomedicine, pesticide, material science and the like.