191469-29-1 Usage
General Description
AGN 195183, also known as bimatoprost, is a prostaglandin analogue used for the treatment of glaucoma and ocular hypertension. It works by decreasing intraocular pressure in the eye, which can help to prevent optic nerve damage and potential vision loss. AGN 195183 is available in the form of eye drops, and is typically used once daily. It is considered to be a safe and effective treatment for these eye conditions, and is well-tolerated by most patients. However, it may cause some side effects, such as eye redness, itching, and darkening of the eyelids or eye color. Overall, AGN 195183 is an important medication for managing glaucoma and ocular hypertension.
Check Digit Verification of cas no
The CAS Registry Mumber 191469-29-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,4,6 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 191469-29:
(8*1)+(7*9)+(6*1)+(5*4)+(4*6)+(3*9)+(2*2)+(1*9)=161
161 % 10 = 1
So 191469-29-1 is a valid CAS Registry Number.
191469-29-1Relevant articles and documents
Synthesis and biological activity of retinoic acid receptor-α specific amides
Beard, Richard L.,Duong, Tien T.,Teng, Min,Klein, Elliott S.,Standevan, Andrew M.,Chandraratna, Roshantha A.S.
, p. 3145 - 3148 (2002)
Retinoids are analogues of all-trans-retinoic acid, a powerful hormone that mediates many fundamental biological processes. Cancer and other serious hyperproliferative diseases are attractive therapeutic targets for retinoids, but the therapeutic use of retinoids is limited due to severe toxicity. We report here the design of retinoid receptor-α specific ligands with growth inhibitory activity in breast cancer cell lines, and which do not cause the cutaneous toxicity associated with the currently available nonselective retinoid agonists.
