191723-68-9

Basic information

• Product Name: H-ILE-AMC TFA
• Synonyms: L-ISOLEUCINE 7-AMIDO-4-METHYLCOUMARIN TRIFLUOROACETATE;L-ISOLEUCINE 7-AMIDO-4-METHYLCOUMARIN, TRIFLUOROACETATE SALT;H-ILE-AMC TFA;ISOLEUCINE-AMC TFA;H-L-Ile-AMC*TFA;L-Isolecucine 7-amido-4- methylcoumarin trifluoroacetate salt
• CAS NO: 191723-68-9
• Molecular Formula: C18H21F3N2O5
• Molecular Weight: 402.36
• Product Categories: Other enzyme inhibitors and activators;Other Enzyme Inhibitors and Activators.
• Mol File: 191723-68-9.mol
• Article Data: 0

Chemical Properties

• Appearance: White to Off-white/Powder
• Storage Temp.: −20°C
• CAS DataBase Reference: H-ILE-AMC TFA(CAS DataBase Reference)
• NIST Chemistry Reference: H-ILE-AMC TFA(191723-68-9)
• EPA Substance Registry System: H-ILE-AMC TFA(191723-68-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 191723-68-9(Hazardous Substances Data)

Usage

Description

H-ILE-AMC TFA, or L-Isoleucine 7-Amido-4-methylcoumarin Trifluoroacetate Salt, is an enzyme substrate that is widely utilized in various applications due to its unique properties. It is characterized by its ability to serve as a substrate for enzymes, particularly aminopeptidases, and its use in analytical and biological studies.

Uses

Used in Analytical Chemistry:
H-ILE-AMC TFA is used as an analytical reagent for the detection and quantification of specific enzymes, such as aminopeptidases, in various samples. Its application in this field is due to the fluorescent properties of the 7-amido-4-methylcoumarin group, which allows for the monitoring of enzyme activity through fluorescence measurements.
Used in Biological Research:
In the field of biological research, H-ILE-AMC TFA is employed as a substrate for studying the activity and function of aminopeptidases. This is particularly useful in understanding the roles these enzymes play in various biological processes and their potential as therapeutic targets.
Used in Food Industry:
H-ILE-AMC TFA is used as a detection tool for the identification and quantification of yeasts and molds in food samples. The presence of these microorganisms can be indicative of spoilage or contamination, making the use of H-ILE-AMC TFA a valuable asset in ensuring food safety and quality.
Used in Pharmaceutical Development:
H-ILE-AMC TFA can also be utilized in the development of new drugs targeting aminopeptidases, which are involved in various diseases, including cancer, inflammation, and neurodegenerative disorders. By using H-ILE-AMC TFA as a substrate, researchers can screen for potential inhibitors or activators of these enzymes, leading to the development of novel therapeutic agents.