191793-76-7

Basic information

• Product Name: (S)-4-Fluoro-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester
• CAS NO: 191793-76-7
• Molecular Weight: 355.366
• Mol File: 191793-76-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-Fluoro-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Fluoro-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester(191793-76-7)
• EPA Substance Registry System: (S)-4-Fluoro-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester(191793-76-7)

Safety Data

• Hazardous Substances Data: 191793-76-7(Hazardous Substances Data)

Upstream product

• 191793-75-6 (S)-N-(9H-fluoren-9-ylmethyloxycarbonyl)-4-hydroxyproline methyl ester 
• 191793-72-3 (S)-4-Fluoro-pyrrolidine-2-carboxylic acid methyl ester 
• 122350-59-8 (2S,4R)-1-(9H-fluoren-9-yl)methyl-2-methyl-4-hydroxypyrrolidine-1,2-dicarboxylate 
• 102774-86-7 9-fluorenylmethyl N-succinimidyl carbonate 
• 191793-73-4 (S)-4-Fluoro-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-methyl ester 
• 88050-17-3 N-Fmoc-trans-4-Hydroxy-L-Proline 

Relevant articles and documents

Fluorinated peptides incorporating a 4-fluoroproline residue as potential inhibitors of HIV protease

N-Fmoc-4-fluoro-L-proline methyl ester was prepared as an attractive synthon for both solid and solution phase peptide synthesis. Its use for the synthesis of Fmoc-Phe-Pro(F)-OMe and Fmoc-Pro(F)-Val-Val-OMe is presented. Direct fluorination with DAST of a