191797-41-8

Basic information

• Product Name: 17-benzyl-3β-hydroxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile
• Synonyms: 17-benzyl-3β-hydroxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile
• CAS NO: 191797-41-8
• Molecular Weight: 391.554
• Mol File: 191797-41-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 17-benzyl-3β-hydroxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 17-benzyl-3β-hydroxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile(191797-41-8)
• EPA Substance Registry System: 17-benzyl-3β-hydroxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile(191797-41-8)

Safety Data

• Hazardous Substances Data: 191797-41-8(Hazardous Substances Data)

Upstream product

• 766-04-1 benzyllithium 
• 40962-87-6 3β-hydroxy-5-androstene-17-keto-16-oxime 
• 639793-16-1 17α-benzyl-16-(hydroxyimino)androst-5-ene-3β,17β-diol 
• 639793-24-1 3β-acetoxy-16-cyano-17-benzyl-16,17-seco-5-androsten-17-one 
• 191797-38-3 (3S,8R,9S,10R,13S,14S,17R)-17-Benzyl-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-cyclopenta[a]phenanthren-16-one oxime 
• 19321-67-6 3β-hydroxy-16-hydroxyiminoandrost-5-en-17-one 
• 103-50-4 dibenzyl ether 

Downstream Products

• 220426-69-7 3β-hydroxy-D-homo-16-amino-17-phenyl-5,16-androstadien-17a-one 
• 904299-31-6 (17S)-17-benzyl-3β,17-dihydroxy-16,17-secoandrost-5-ene-16-nitrile 

Relevant articles and documents

Synthesis and biological activity of some 17a-substituted homolactones of androst-5-ene derivatives

Some new 17a-homolactones were prepared from 3β-hydroxy-16- (hydroxyimino)androst-5-en-17-one (1) as a starting compound, which was transformed first to the corresponding 17α-phenyl and 17α-benzyl derivatives 2 and 3. The structure of compound 3 was confi

A novel rearrrangement of steroidal α-hydroxy grimes

By the action of acidic titanium trichloride upon 16-oximino-17α-benzyl-17α-hydroxy derivatives in the androstane and estrane series the 16-oxo-17-β-benzyl-17α-hydroxy derivatives 6 and 7 with inversed configuration at C17 were obtained. A mechanism for this novel rearrangement is proposed.