19191-91-4 Usage
Description
L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL, also known as 1,2-dioctanoyl-sn-glycero-3-phosphocholine (C8PC), is a phospholipid compound with a variety of physical properties. It is a part of the Phosphatidylcholine products offered by Avanti, which are designed to provide compounds with different characteristics such as short chain, saturated, multi-unsaturated, and mixed acid PC's. This specific compound is water-soluble and hygroscopic, and it is purified by high-performance liquid chromatography (HPLC) to ensure quality and protect it from oxidation and hydrolysis.
Uses
Used in Analytical Chemistry:
L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL is used as a substrate for studying the analytical capabilities of various methods to determine water-soluble phospholipids containing choline (wCh-PL). It is also used to study the behavior of its analytical signal in a synthetic serum matrix (data-Trol).
Used in Bicellar Model Studies:
L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL is used as a bicellar model to study its phase behavior, which can provide insights into the structural and dynamic properties of lipid bilayers and their interactions with other molecules.
Used in Pharmaceutical Research:
L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL is used to form a lipid film to study its effect on P-glycoprotein's (P-gp's) activity. This is important for understanding the transport of drugs across cell membranes and the development of more effective drug delivery systems. It is also used to compare its effect with other substances like TWEEN 80 and Cremophor EL.
Biochem/physiol Actions
Phosphatidylcholine?(PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.
Check Digit Verification of cas no
The CAS Registry Mumber 19191-91-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,1,9 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19191-91:
(7*1)+(6*9)+(5*1)+(4*9)+(3*1)+(2*9)+(1*1)=124
124 % 10 = 4
So 19191-91-4 is a valid CAS Registry Number.
19191-91-4Relevant articles and documents
Stereochemical Analysis of Glycerophospholipids by Vibrational Circular Dichroism
Taniguchi, Tohru,Manai, Daisuke,Shibata, Masataka,Itabashi, Yutaka,Monde, Kenji
supporting information, p. 12191 - 12194 (2015/10/12)
The stereochemistry of glycerophospholipids (GPLs) has been of interest for its roles in the evolution of life and in their biological activity. However, because of their structural complexity, no convenient method to determine their configuration has been reported. In this work, through the first systematic application of vibrational circular dichroism (VCD) spectroscopy to various diacylated GPLs, we have revealed that their chirality can be assigned by the sign of a VCD exciton couplet generated by the interaction of two carbonyl groups. This paper also presents spectroscopic evidence for the stereochemistry of GPLs isolated from bacteria, eukaryotes, and mitochondria.
