191990-34-8

Basic information

• Product Name: 5-[(thiocholesteryl)thio]-2-nitrobenzoic acid
• Synonyms: 5-[(thiocholesteryl)thio]-2-nitrobenzoic acid
• CAS NO: 191990-34-8
• Molecular Weight: 599.899
• Mol File: 191990-34-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[(thiocholesteryl)thio]-2-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(thiocholesteryl)thio]-2-nitrobenzoic acid(191990-34-8)
• EPA Substance Registry System: 5-[(thiocholesteryl)thio]-2-nitrobenzoic acid(191990-34-8)

Safety Data

• Hazardous Substances Data: 191990-34-8(Hazardous Substances Data)

Upstream product

• 69-78-3 5,5'-dithiobis-(2-nitrobenzoic acid) 
• 1249-81-6 thiocholesterol 

Relevant articles and documents

Cholesterol modification of (bio)polymers using UV-vis traceable chemistry in aqueous solutions

Cholesterol modification of synthetic and biological polymers is achieved using of thiocholesterol (TC) and thiol-disulfide exchange. TC is reacted with Ellman's reagent to produce a mixed disulfide (TC-ER) which is activated towards thiol-disulfide exchange. TC-ER is used to obtain an inclusion complex with methyl-β-cyclodextrin, which is then employed to achieve cholesterol functionalization of a model peptide, synthetic polymers, and physical hydrogels based on poly(vinyl alcohol). It is anticipated that the established techniques will significantly broaden the use of cholesterol in bio- and nanotechnology and specifically biomedicine.