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19202-27-8

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19202-27-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 19202-27-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,0 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19202-27:
(7*1)+(6*9)+(5*2)+(4*0)+(3*2)+(2*2)+(1*7)=88
88 % 10 = 8
So 19202-27-8 is a valid CAS Registry Number.

19202-27-8Relevant articles and documents

Design, synthesis and activity evaluation of N-(pyridin-4-yl) salicylamides as antimycobacterial agents

Dian, He,Zhou, De-Bin,Mou, Jian-Ping,Yang, Zhu-Qing,Zhong, Jia,Ding, Xiao-Quan,Li, Chong,Wang, Xiao-Hong,Zhang, Jian-Gang

, p. 7269 - 7275 (2015/04/22)

A series of N-(pyridin-4-yl) salicylamides derivatives were prepared through acylation of the corresponding acetylsalicyloyl chlorides with substituted 4-amino-pyridines. These compounds were evaluated in vitro for antimycobacterial activities against Myc

Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats

Dhanya, Raveendra-Panickar,Sidique, Shyama,Sheffler, Douglas J.,Nickols, Hilary Highfield,Herath, Ananda,Yang, Li,Dahl, Russell,Ardecky, Robert,Semenova, Svetlana,Markou, Athina,Conn, P. Jeffrey,Cosford, Nicholas D. P.

experimental part, p. 342 - 353 (2011/03/18)

The modification of 3′-((2-cyclopentyl-6,7-dimethyl-1-oxo-2,3- dihydro-1H-inden-5-yloxy)methyl)biphenyl-4-carboxylic acid (BINA, 1) by incorporating heteroatoms into the structure and replacing the cyclopentyl moiety led to the development of new mGluR2 positive allosteric modulators (PAMs) with optimized potency and superior druglike properties. These analogues are more potent than 1 in vitro and are highly selective for mGluR2 vs other mGluR subtypes. They have significantly improved pharmacokinetic (PK) properties, with excellent oral bioavailability and brain penetration. The benzisothiazol-3-one derivative 14 decreased cocaine self-administration in rats, providing proof-of-concept for the use of mGluR2 PAMs for the treatment of cocaine dependence.

Structure-activity relationships of non-peptide vasopressin V(1a) antagonists: 1-(1-multi-substituted benzoyl 4-piperidyl)-3,4-dihydro-2(1H)- quinolinones

Kondo,Ogawa,Nakaya,Tominaga,Yabuuchi

, p. 725 - 733 (2007/10/03)

During our systematic studies on the arginine vasopressin receptor V(1a)- antagonistic activity of 1-(1-benzoyl substituted 4-piperidyl)-3,4-dihydro- 2(1H)-quinolinones, we found a general substituent effect on the benzene ring. Hydrogen-bonding ability a

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