192070-28-3

Basic information

• Product Name: (2S,4R)-4-(4-Benzyloxy-benzyl)-2-tert-butyl-4-(3-methyl-but-2-enyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester
• CAS NO: 192070-28-3
• Molecular Weight: 491.627
• Mol File: 192070-28-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4R)-4-(4-Benzyloxy-benzyl)-2-tert-butyl-4-(3-methyl-but-2-enyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-4-(4-Benzyloxy-benzyl)-2-tert-butyl-4-(3-methyl-but-2-enyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester(192070-28-3)
• EPA Substance Registry System: (2S,4R)-4-(4-Benzyloxy-benzyl)-2-tert-butyl-4-(3-methyl-but-2-enyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester(192070-28-3)

Safety Data

• Hazardous Substances Data: 192070-28-3(Hazardous Substances Data)

Upstream product

• 5544-60-5 4-(benzyloxy)benzyl bromide 
• 192070-21-6 (2S,4S)-2-tert-Butyl-4-(3-methyl-but-2-enyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester 

Downstream Products

• 192070-45-4 (S)-2-[(R)-5-(4-Benzyloxy-benzyl)-5-(3-methyl-but-2-enyl)-4-oxo-4,5-dihydro-1H-pyrrol-3-yl]-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid methyl ester 
• 192070-34-1 (R)-2-Allyloxycarbonylamino-2-(4-benzyloxy-benzyl)-5-methyl-hex-4-enoic acid methyl ester 
• 192070-40-9 (R)-2-Amino-2-(4-benzyloxy-benzyl)-5-methyl-hex-4-enoic acid methyl ester 

Relevant articles and documents

A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains

To access mimics of peptide β-strands (1), scalemic 3,5,5-trisubstituted pyrrolin-4-ones bearing the tyrosine, serine, and lysine side-chains have been generated via cyclization of metalated imino esters and deprotection. The functionalized imino esters were prepared by asymmetric alkylation of a common oxazolidinone precursor (2) derived from L-rhenylglycine.