19225-97-9

Basic information

• Product Name: 1,2-dimethyl-5-phenyl-1H-imidazole
• Synonyms: 1,2-dimethyl-5-phenyl-1H-imidazole
• CAS NO: 19225-97-9
• Molecular Weight: 172.23
• Mol File: 19225-97-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 1,2-dimethyl-5-phenyl-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dimethyl-5-phenyl-1H-imidazole(19225-97-9)
• EPA Substance Registry System: 1,2-dimethyl-5-phenyl-1H-imidazole(19225-97-9)

Safety Data

• Hazardous Substances Data: 19225-97-9(Hazardous Substances Data)

Upstream product

• 1739-84-0 1,2-dimethyl-1H-imidazole 
• 108-86-1 bromobenzene 
• 591-50-4 iodobenzene 
• 108-90-7 chlorobenzene 
• 24134-09-6 5-bromo-1,2-dimethyl-1H-imidazole 
• 78-67-1 2,2'-azobis(isobutyronitrile) 
• 71-43-2 benzene 

Relevant articles and documents

Method for catalyzing direct arylation of imidazole compound by using palladium complex

The invention relates to a method for catalyzing direct arylation of an imidazole compound by using a palladium complex, which comprises the following steps: in the presence of alkali, taking the imidazole compound and aryl halide as raw materials, taking

Dimetallic Palladium-NHC Complexes: Synthesis, Characterization, and Catalytic Application for Direct C?H Arylation Reaction of Heteroaromatics with Aryl Chlorides

A series of dimetallic palladium(II)-NHC complexes comprised of 1,4-naphthalenyl or 9,10-anthracenyl spacer sandwiched between two imidazole rings was successfully synthesized. These complexes were characterized by 1H and 13C{1H} NMR spectroscopy and elemental analysis. The structures of two dimetallic palladium complexes and a related mononuclear palladium complex to be used for comparative studies were further characterized by X-ray diffraction. The dimetallic palladium complex with the 9,10-anthracenyl linker was very efficient in catalyzing direct C?H arylation reactions of heteroaromatic compounds (imidazoles, imidazo[1,2-a]pyridine, and thioazole) with a broad range of aryl chlorides, employing a mild monopalladium loading of 1.5 mol%.It allows for the effective use of aryl chlorides to prepare arylated heterocycles, previously only accessible with the more reactive bromide counterparts. Importantly, the catalytic activity of the dimetallic precatalyst was found to be higher than that of an analogous mononuclear complex. (Figure presented.).

Imidazole-aryl coupling reaction via C[sbnd]H bond activation catalyzed by palladium supported on modified magnetic reduced graphene oxide in alkaline deep eutectic solvent

By employing reusable heterogeneous catalyst, modified magnetic reduced graphene oxide-supported palladium catalyst (MRGO@ DAP- AO-Pdll), the regioselective C-5 arylation of imidazoles via C[sbnd]H bond activation pathway for the preparation of