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192374-17-7

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  • 6-carboxy-3',6'-di-O-pivaloylfluorescein, 5-carboxyfluorescein dipivalate, 6-carboxyfluorescein-3',6'-dipivalat, 6-carboxyfluorescein dipivaloate, 6-carboxyfluorescein dipivalate

    Cas No: 192374-17-7

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192374-17-7 Usage

Description

6-CARBOXYFLUORESCEIN DIPIVALATE, also known as 3'',6''-Bis(2,2-dimethyl-1-oxopropoxy)-3-oxospiro[isobenzofuran-1(3H),9''-[9H]xanthene]-6-carboxylic Acid, is a synthetic compound with fluorescent properties. It is characterized by its ability to emit fluorescence upon excitation, making it a valuable tool in various scientific and medical applications.

Uses

Used in Biomedical Research:
6-CARBOXYFLUORESCEIN DIPIVALATE is used as a fluorescent tracer for its ability to emit fluorescence upon excitation. This property makes it a useful tool in the field of biomedical research, particularly in the development of molecular beacon probes for the detection of specific cells or molecules.
Used in Cancer Detection:
In the field of cancer research, 6-CARBOXYFLUORESCEIN DIPIVALATE is used as a reactant in the specific molecular beacon probe for the detection of human prostate cancer cells. Its fluorescent properties allow for the precise identification and tracking of these cells, aiding in the early diagnosis and treatment of prostate cancer.
Used in Drug Delivery Systems:
Although not explicitly mentioned in the provided materials, 6-CARBOXYFLUORESCEIN DIPIVALATE's fluorescent properties could also be utilized in drug delivery systems. By incorporating this compound into drug formulations, researchers can track the distribution and release of therapeutic agents within the body, potentially improving the efficacy and safety of drug treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 192374-17-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,3,7 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 192374-17:
(8*1)+(7*9)+(6*2)+(5*3)+(4*7)+(3*4)+(2*1)+(1*7)=147
147 % 10 = 7
So 192374-17-7 is a valid CAS Registry Number.

192374-17-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-CARBOXYFLUORESCEIN DIPIVALATE

1.2 Other means of identification

Product number -
Other names 6-carboxyfluorescein dipivolate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:192374-17-7 SDS

192374-17-7Relevant articles and documents

Optical Manipulation of Subcellular Protein Translocation Using a Photoactivatable Covalent Labeling System

Kowada, Toshiyuki,Arai, Keisuke,Yoshimura, Akimasa,Matsui, Toshitaka,Kikuchi, Kazuya,Mizukami, Shin

supporting information, p. 11378 - 11383 (2021/04/09)

The photoactivatable chemically induced dimerization (photo-CID) technique for tag-fused proteins is one of the most promising methods for regulating subcellular protein translocations and protein–protein interactions. However, light-induced covalent protein dimerization in living cells has yet to be established, despite its various advantages. Herein, we developed a photoactivatable covalent protein-labeling technology by applying a caged ligand to the BL-tag system, a covalent protein labeling system that uses mutant β-lactamase. We further developed CBHD, a caged protein dimerizer, using caged BL-tag and HaloTag ligands, and achieved light-induced protein translocation from the cytoplasm to subcellular regions. In addition, this covalent photo-CID system enabled quick protein translocation to a laser-illuminated microregion. These results indicate that the covalent photo-CID system will expand the scope of CID applications in the optical manipulation of cellular functions.

POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES

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Page/Page column 53, (2008/06/13)

The present invention concerns methods of polymerase independent template directed elongation of polynucleotides, nucleotide building blocks used in these methods as well as the use of the methods and building blocks for the determination of nucleotide sequences, in particular for the determination of SNPs, base modifications, mutations, rearrangements and methylation patterns.

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