192456-37-4Relevant articles and documents
5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of β-amyloid protein production
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, (2008/06/13)
A series of 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives of Formula I have been synthesized. STR1 As inhibitors of the production of β-amyloid protein from β-amyloid precursor protein, these compounds are expected to be effective in treating patients suffering from or susceptible to conditions or disorders linked to brain accumulation of β-amyloid protein; e.g., Alzheimer's Disease and Down's Syndrome.