192463-40-4 Usage
Description
(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE is a chiral phosphine ligand that is structurally characterized by its paracyclophane core with two diphenylphosphino groups attached at the 4 and 12 positions. This unique structure endows it with specific properties that make it valuable in various applications, particularly in the field of catalysis.
Uses
Used in Pharmaceutical Industry:
(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE is used as an efficient ligand for asymmetric hydrogenation reactions, which are crucial in the synthesis of various pharmaceutical compounds. Its ability to selectively catalyze these reactions allows for the production of enantiomerically pure compounds, which are essential for the development of effective and safe drugs.
Used in Chemical Synthesis:
In the field of chemical synthesis, (R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE is used as a versatile ligand for various catalytic applications. Its unique structure enables it to facilitate the hydrogenation of dehydroamino acids, methyl esters, and ketones, which are key steps in the synthesis of complex organic molecules. This ligand's high selectivity and efficiency make it a valuable tool for chemists in the development of new compounds and materials.
Used in Research and Development:
(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE is also utilized in research and development settings, where its unique properties are explored for potential applications in catalysis and other chemical processes. Its ability to enhance the selectivity and efficiency of various reactions makes it an important compound for scientists working on the development of new technologies and processes in the chemical industry.
Reaction
Ligand for rhodium-catalyzed enantioselective hydroboration of cyclopropenes.
Ligand for iridium-catalyzed enantioselective [2+2] cycloaddition of oxabicyclic alkenes with terminal alkynes.
Ligand for the palladium-catalyzed enantioselective hydroxycarbonylation and alkoxycarbonylation of alkenes.
Ligand for the palladium-catalyzed amides synthesis via C(sp3 )–H bond functionalization and CO insertion.
Ligand for iridium-catalyzed diene hydrohydroxymethylation.
Check Digit Verification of cas no
The CAS Registry Mumber 192463-40-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,4,6 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 192463-40:
(8*1)+(7*9)+(6*2)+(5*4)+(4*6)+(3*3)+(2*4)+(1*0)=144
144 % 10 = 4
So 192463-40-4 is a valid CAS Registry Number.
InChI:InChI=1/C40H34P2/c1-5-13-35(14-6-1)41(36-15-7-2-8-16-36)39-29-31-21-25-33(39)27-23-32-22-26-34(28-24-31)40(30-32)42(37-17-9-3-10-18-37)38-19-11-4-12-20-38/h1-22,25-26,29-30H,23-24,27-28H2
