192518-28-8Relevant articles and documents
Modelisation, synthesis and anti-HIV activities of N,N,N',N',N'-pentakis-tetraazamacrocycles salts derivatives
Trabaud,Dessolin,Vlieghe,Bouygues,Chermann,Camplo,Kraus
, p. 1353 - 1358 (1997)
The syntheses and the anti-HIV activities of new N,N,N',N',N'-pentakistetraazamacrocycles salts analogues are described. From computer modeling studies, it was found that zinc coordination capacity of these pentakis derivatives was larger than the one of the corresponding tetrakis analogues. This suggest that a metal chelation energy could be a criteria to design novel anti-HIV polyazamacrocycles.
