19256-46-3

Basic information

• Product Name: 2-deuteriochlorobenzene
• Synonyms: 2-deuteriochlorobenzene
• CAS NO: 19256-46-3
• Molecular Weight: 113.551
• Mol File: 19256-46-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-deuteriochlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-deuteriochlorobenzene(19256-46-3)
• EPA Substance Registry System: 2-deuteriochlorobenzene(19256-46-3)

Safety Data

• Hazardous Substances Data: 19256-46-3(Hazardous Substances Data)

Upstream product

• 811-98-3 d⁽⁴⁾-methanol 
• 108-90-7 chlorobenzene 
• 694-80-4 2-bromo-1-chlorobenzene 
• 615-41-8 2-iodochlorobenzene 

Downstream Products

• 22070-00-4 o-deuterioiodobenzene 
• 22069-99-4 1-bromo-2-deuterobenzene 
• 1373945-02-8 2-(tert-butyl)-bis(2-deuteriophenyl)silyl-3-methoxyphenyl trifluoromethanesulfonate 

Relevant articles and documents

Palladium-Assisted "Aromatic Metamorphosis" of Dibenzothiophenes into Triphenylenes

Abstract Two new palladium-catalyzed reactions of aromatic sulfur compounds enabled the conversion of dibenzothiophenes into triphenylenes in four steps. This transformation of one aromatic framework into another consists of 1) 4-chlorobutylation of the dibenzothiophene to form the corresponding sulfonium salt, 2) palladium-catalyzed arylative ring opening of the sulfonium salt with a sodium tetraarylborate, 3) an intramolecular SN2 reaction to form a teraryl sulfonium salt, and 4) palladium-catalyzed intramolecular C-S/C-H coupling through electrophilic palladation. Symmetrical as well as unsymmetrical triphenylenes of interest were synthesized in a tailor-made fashion in satisfactory overall yields. A change of heart: The invention of two palladium-catalyzed arylation reactions of organosulfur compounds enabled the transformation of dibenzothiophenes into triphenylenes and thus a fundamental change in the core aromatic structure (see scheme). Both symmetrical and unsymmetrical triphenylenes were synthesized in a tailor-made fashion in satisfactory overall yield.

Regioselective Dihydroarene Oxide Formation during ortho-Hydroxylation of Halogenobenzenes by Fungi

ortho-Hydroxylation of chloro- and bromo-benzene occurred in the presence of growing cultures of the fungi Rhizopus arrhizus, Rhizopus stolonifer, and Cunninghamella elegans.The absence of a primary kinetic isotope effect and the presence of the NIH shift are consistent with dihydroarene oxides being initial metabolites.N.m.r. analysis of the deuterium-labelled o-halogenophenol products suggested that enzyme-catalysed epoxidation occurs preferentially at the 2,3-bond.