192642-82-3

Basic information

• Product Name: 6-broMo-[1,2,3]triazolo[1,5-a]pyridine
• Synonyms: 6-broMo-[1,2,3]triazolo[1,5-a]pyridine;6-bromotriazolo[1,5-a]pyridine
• CAS NO: 192642-82-3
• Molecular Formula: C₆H₄BrN₃
• Molecular Weight: 198.02006
• Mol File: 192642-82-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.89±0.1 g/cm3(Predicted)
• PKA: 0.35±0.30(Predicted)
• CAS DataBase Reference: 6-broMo-[1,2,3]triazolo[1,5-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-broMo-[1,2,3]triazolo[1,5-a]pyridine(192642-82-3)
• EPA Substance Registry System: 6-broMo-[1,2,3]triazolo[1,5-a]pyridine(192642-82-3)

Safety Data

• Hazardous Substances Data: 192642-82-3(Hazardous Substances Data)

Upstream product

• 192642-97-0 (E,Z)-N’-((5-bromopyridin-2-yl)methylene)-4-methylbenzene-sulfonohydrazide 
• 31181-90-5 5-bromo-pyridine-2-carbaldehyde 
• 88139-91-7 (5-bromopyridin-2-yl)methanol 
• 31181-74-5 (5-bromopyridin-2-yl)methyl acetate 
• 31181-64-3 5-bromo-2-methyl-pyridine-N-oxide 

Downstream Products

• 1024742-01-5 6-(p-tolylthio)[1,2,3]triazolo[1,5-a]pyridine 

Relevant articles and documents

PYRAZOLO[1,5-D][1,2,4]TRIAZINE-5(4H)-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY

The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of a disease or disorder that is associated with NLRP3 inflammasome activity.

Copper-catalyzed aerobic carboxygenation and N-arylation of [1,2,3]triazolo[1,5-a]pyridines towards pyridinium triazolinone ylides

Copper-catalyzed aerobic oxyarylation of [1,2,3]triazolo[1,5-a]pyridines is developed. Notably molecular oxygen was utilized as one of the reagents and the transformation resulted in the formation of novel pyridinium triazolinone ylides. A basic mechanism for the one-pot process is proposed and further functionalization of the ylidic products were also presented.

Triazolopyridines. 18.1 nucleophilic substitution reactions on triazolopyridines; a new route to 2,2'-Bipyridines

The synthesis of some 5-, 6-, and 7-halogenotriazolopyridines is described and their reactions with nucleophiles. The formation or 7,7'-bitriazolopyridines provides a new synthesis of 2,2'-bipyridines.