192815-75-1

Basic information

• Product Name: 3-Morpholinone, 4-(2-diazo-1,3-dioxobutyl)-5-phenyl-, (R)-
• CAS NO: 192815-75-1
• Molecular Formula: C14H13N3O4
• Molecular Weight: 287.275
• Mol File: 192815-75-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Morpholinone, 4-(2-diazo-1,3-dioxobutyl)-5-phenyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Morpholinone, 4-(2-diazo-1,3-dioxobutyl)-5-phenyl-, (R)-(192815-75-1)
• EPA Substance Registry System: 3-Morpholinone, 4-(2-diazo-1,3-dioxobutyl)-5-phenyl-, (R)-(192815-75-1)

Safety Data

• Hazardous Substances Data: 192815-75-1(Hazardous Substances Data)

Upstream product

• 192815-71-7 (5R)-5-phenylmorpholin-3-one 
• 56613-80-0 D-2-phenylglycinol 

Downstream Products

• 192815-78-4 (R)-4-(2-Diazo-acetyl)-5-phenyl-morpholin-3-one 

Relevant articles and documents

Cycloadditions of chiral carbonyl ylides with imine dipolarophiles as a route to enantiomerically pure α-amino-β-hydroxy acids

The preparation of enantiomerically pure threo-β-amino-α-hydroxy acids via 1,3-dipolar cycloadditions of imine dipolarophiles with the chiral isomuenchnone derived from (5R)-5-phenylmorpholin-3-one 1 is described. The cycloadducts were obtained with excellent diastereofacial- and exo-selectivity. Subsequent hydrolysis and chemoselective exocyclic amide cleavage afforded the threo-β-amino-α-hydroxy acids with recovery of the initial chiral auxiliary.