192940-83-3

Basic information

• Product Name: 2-chloro-3,4,5-trimethoxybenzoic acid
• Synonyms: 2-chloro-3,4,5-trimethoxybenzoic acid
• CAS NO: 192940-83-3
• Molecular Weight: 246.647
• Mol File: 192940-83-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-chloro-3,4,5-trimethoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3,4,5-trimethoxybenzoic acid(192940-83-3)
• EPA Substance Registry System: 2-chloro-3,4,5-trimethoxybenzoic acid(192940-83-3)

Safety Data

• Hazardous Substances Data: 192940-83-3(Hazardous Substances Data)

Upstream product

• 118-41-2 Eudesmic acid 
• 192863-64-2 2-chloro-3,4,5-trimethoxybenzoic acid methyl ester 

Downstream Products

• 1310849-07-0 (2-chloro-3,4,5-trimethoxyphenyl)(furan-2-yl)methanone 
• 1310849-30-9 (2-chloro-3,4,5-trihydroxyphenyl)(furan-2-yl)methanone 
• 1310849-00-3 C₁₀H₁₀Cl₂O₄ 
• 61948-85-4 3,4,5-trimethoxyanthranilic acid 

Relevant articles and documents

Compound and application thereof

The invention discloses a compound and application thereof. The compound is the compound shown in the formula (I) or a stereoisomer or a pharmaceutical acceptable salt or solvate or a prodrug of the compound shown in the formula (I). The compound can restrain tumor cell proliferation through the effect RRM2, and restrain tumor stem cell regeneration, thereby being effectively used for preparing medicine for preventing or treating proliferative diseases and particularly anti-cancer medicine.

Synthesis and in vitro protein tyrosine kinase inhibitory activity of furan-2-yl(phenyl)methanone derivatives

A series of novel furan-2-yl(phenyl)methanone derivatives were synthesized, and their structures were established on the basis of 1H-NMR, 13C-NMR and mass spectral data. All the prepared compounds were screened for their in vitro protein tyrosine kinase inhibitory activity and several new derivatives exhibited promising activity, which, in some cases, was identical to, or even better than that of genistein, a positive reference compound. The preliminary structure-activity relationships of these compounds were investigated and are discussed.

Novel substituted 4-(1H-benzimidazol-2-yl) [1,4]diazepanes useful for the treatment of allergic diseases

The present invention relates to novel 4-(1H-benzimidazol-2-yl)[1,4]diazepane derivatives of formula and stereoisomers thereof, and pharmaceutically acceptable salts thereof which are useful as histamine receptor antagonists and tachykinin receptor antagonist. Such antagonists are useful in the treatment of allergic rhinitis, including seasonal rhinitis and sinusitis; inflammatory bowel diseases, including Crohn's disease and ulcerative colitis; asthma; bronchitis; and emesis.