19295-57-9

Basic information

• Product Name: 3-hydroxy-2,2-dimethylpropanenitrile
• Synonyms: 3-hydroxy-2,2-dimethylpropanenitrile;propanenitrile, 3-hydroxy-2,2-dimethyl-;3-hydroxy-2,2-dimethyl-propionitrile
• CAS NO: 19295-57-9
• Molecular Formula: C₅H₉NO
• Molecular Weight: 99
• Mol File: 19295-57-9.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 86-87 °C(Press: 18 Torr)
• Appearance: /
• Density: 0.971±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.75±0.10(Predicted)
• CAS DataBase Reference: 3-hydroxy-2,2-dimethylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-2,2-dimethylpropanenitrile(19295-57-9)
• EPA Substance Registry System: 3-hydroxy-2,2-dimethylpropanenitrile(19295-57-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 19295-57-9(Hazardous Substances Data)

Usage

General Description

3-Hydroxy-2,2-dimethylpropanenitrile is a synthetic chemical compound that belongs to the family of hydroxynitriles. This type of compound is characterized by the presence of a nitrile group (-CN) and a hydroxyl group (-OH). The structural formula of 3-hydroxy-2,2-dimethylpropanenitrile indicates that it also includes two methyl groups (-CH3). The presence of hydroxyl and nitrile groups may suggest that it has both acidic and basic characteristics. While the exact uses of 3-hydroxy-2,2-dimethylpropanenitrile may depend on specific industrial or scientific needs, generally, similar compounds are often employed in organic synthesis, such as in the production of pharmaceuticals, adhesives, polymers and dyes.

Upstream product

• 36559-87-2 3-hydroxy-2,2-dimethylpropionaldoxime 
• 50-00-0 formaldehyd 
• 78-82-0 Isobutyronitrile 
• 558-38-3 2-chloro-2-methyl-1-propanol 
• 143-33-9 sodium cyanide 
• 41296-71-3 3-acetoxy-2,2-dimethyl-propionitrile 
• 597-31-9 2,2-dimethyl-3-hydroxypropionaldehyde 
• 201230-82-2 carbon monoxide 
• 126-98-7 methacrylonitrile 
• 630-18-2 tert-butyl isocyanide 
• 22426-30-8 2-cyano-2-methylpropanoic acid 
• 1572-98-1 2-cyano-2-methyl-propionic acid ethyl ester 
• 72291-30-6 methyl 2,2-dimethyl-cyanoacetate 

Downstream Products

• 4835-90-9 3-Hydroxy-2,2-dimethylpropanoic acid 
• 22426-30-8 2-cyano-2-methylpropanoic acid 
• 26734-09-8 3-amino-2,2-dimethylpropan-1-ol 
• 157736-55-5 2,2-dimethyl-<<4-methylphenylsulfonyl>oxy>propanenitrile 
• 19816-92-3 3,3-dimethyl azetidine 
• 79201-18-6 3,3-dimethyl-N-<4-methylphenylsulfonyl>azetidine 
• 85289-24-3 5,5-Dimethyl-2-phenoxy-[1,3,2]oxazaphosphinane 2-oxide 
• 85289-25-4 5,5-Dimethyl-2-phenoxy-[1,3,2]oxazaphosphinane 2-sulfide 
• 132259-96-2 2,2-dimethyl-3-(benzyloxy)propionitrile 
• 99705-29-0 3-methoxy-2,2-dimethylpropanenitrile 
• 863399-82-0 3-(4-fluorobenzyloxy)-2,2-dimethylpropionitrile 
• 1432122-84-3 N⁴-phenoxyacetyl-2’-O-(2-cyano-2,2-dimethylethanimine-N-oxymethyl)cytidine 
• 1432122-87-6 N⁶-phenoxyacetyl-2’-O-(2-cyano-2,2-dimethylethanimine-N-oxymethyl)adenosine 
• 1432122-90-1 N²-phenoxyacetyl-2’-O-(2-cyano-2,2-dimethylethanimine-N-oxymethyl)guanosine 

Relevant articles and documents

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BENZETHERS AND ANILINES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF

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Method for preparing 2-amino-2-methyl-1-propanol

The invention relates to a method for preparing 2-amino-2-methyl-1-propanol. The method comprises the following steps: 1) enabling 2-chloropropane and sodium cyanide to react to generate 2-methyl propionitrile; 2) performing aldol condensation reaction on the 2-methyl propionitrile and formaldehyde so as to generate 2,2-dimethyl-3-hydroxy propionitrile; 3) performing hydrolysis reaction on 2,2-dimethyl-3-hydroxy propionitrile so as to generate 2,2-dimethyl-3-hydroxy propanamide; and 4) performing Hofmann degradation on the 2,2-dimethyl-3-hydroxy propanamide, thereby obtaining 2-amino-2-methyl-1-propanol. The method is cheap and easy in obtaining of raw materials of different steps, simple in reaction process, free of hash reaction condition, remarkable in cost advantage, high in yield, low in pollution and easy in product purification.