193086-15-6

Basic information

• Product Name: Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 193086-15-6
• Molecular Formula: C₉H₁₉NO₃
• Molecular Weight: 189.25206
• Product Categories: N-BOC
• Mol File: 193086-15-6.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)(193086-15-6)
• EPA Substance Registry System: Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)(193086-15-6)

Safety Data

• Hazardous Substances Data: 193086-15-6(Hazardous Substances Data)

Upstream product

• 96-20-8 2-aminobutanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1247018-30-9 C₁₆H₂₁NO₃ 

Downstream Products

• 193086-17-8 {1-[(methyl-{1-[methyl-(1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-2-naphthalen-2-yl-ethyl}-carbamoyl)-methoxymethyl]-propyl}-carbamic acid tert-butyl ester 
• 138374-00-2 2-(N-tert-butoxycarbonyl)-1,2-diaminobutane hydrochloride 
• 96-20-8 2-aminobutanol 
• 346690-97-9 N-(tert-butoxycarbonyl)-2-aminobutanal 
• 304021-07-6 tert-butyl ((3R)-2-hydroxypentan-3-yl)carbamate 

Relevant articles and documents

Design of Selenium-Based Chiral Chemical Probes for Simultaneous Enantio- and Chemosensing of Chiral Carboxylic Acids with Remote Stereogenic Centers by NMR Spectroscopy

Selenium-based enantiopure chiral chemical probes have been designed in a modular way starting from available amino alcohols. The probes developed were found to be efficient in chemoselective interaction with carboxylic functions of chiral substrates leading to diastereomeric amide formation and in sensing α-, β-, and remote (up to seven bonds away from the carboxylic group) chiral centers by using77Se NMR spectroscopy. As a result, it was possible to determine the enantiomeric ratio of structurally diverse individual chiral acids including polyfunctional compounds and drugs with high accuracy. An approach to analyzing the crude reaction mixtures has been successfully developed by using bifunctional selenium- and fluorine-containing chiral probes. More importantly, it was revealed that, based on the77Se NMR data obtained, it is possible to obtain primary information about the location and nature of the substituents at the chiral center (chemo- and enantiosensing), which can simplify the structural elucidation of complex compounds. The derivatization procedure takes as little as 5 min and can be performed directly in an NMR tube followed by NMR measurements without any isolation and purification steps.

CALPAIN-2 SELECTIVE INHIBITOR COMPOUNDS FOR TREATMENT OF GLAUCOMA

Compounds of Formula (I) are provided including for treatment of disorders such as glaucoma.

An efficient copper-catalysed pyrrole synthesis

Copper-catalysed cyclisations of β-hydroxyhomopropargylic sulfonamides can be carried out using copper(II) acetate in hot toluene to provide generally excellent yields of the corresponding pyrroles. ARKAT-USA, Inc.