193280-13-6

Basic information

• Product Name: (1R,3S)-(+)-3-(Trifluoromethyl)camphonanoyl fluoride
• CAS NO: 193280-13-6
• Molecular Weight: 226.214
• Mol File: 193280-13-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,3S)-(+)-3-(Trifluoromethyl)camphonanoyl fluoride(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3S)-(+)-3-(Trifluoromethyl)camphonanoyl fluoride(193280-13-6)
• EPA Substance Registry System: (1R,3S)-(+)-3-(Trifluoromethyl)camphonanoyl fluoride(193280-13-6)

Safety Data

• Hazardous Substances Data: 193280-13-6(Hazardous Substances Data)

Upstream product

• 124-83-4 D-(+)-camphoric acid 

Relevant articles and documents

Selective fluorination of (1R,3S)-(+)-camphoric acid with sulphur tetrafluoride. Preparation of fluorinated optically active derivatives of 1,2,2-trimethylcyclopentane

Treatment of (1R,3S)-(+)-camphoric acid (1) with sulphur tetrafluoride at ambient temperature gives, in general, three products: 1,2,2-trimethyl-3-trifluoromethyl-1-cyclopentanoyl fluoride (2), 2,2,4,4-tetrafluoro-1,8,8-trimethyl-3-oxa-bicyclo[3.2.1]octane (3) and camphoroyl difluoride (4). The ratio of products strongly depends on the reaction time. Alkaline hydrolysis of (2) gives 1,2,2-trimethyl-3-trifluoromethyl-1-cyclopentanecarboxylic acid (5), quantitatively. All products exhibit optical activity.