19346-45-3 Usage
Description
2-Fluoro-6-methyl-3-nitropyridine is an organic compound characterized by the presence of a fluorine atom at the 2nd position, a methyl group at the 6th position, and a nitro group at the 3rd position on a pyridine ring. It serves as a key intermediate in the synthesis of various pharmaceuticals and chemical compounds.
Uses
Used in Pharmaceutical Synthesis:
2-Fluoro-6-methyl-3-nitropyridine is used as a synthetic intermediate for the production of various pharmaceutical compounds. Its unique structure allows for the creation of molecules with specific biological activities, making it a valuable building block in the development of new drugs.
Used in Chemical Research:
In the field of chemical research, 2-Fluoro-6-methyl-3-nitropyridine is utilized as a starting material for the synthesis of novel compounds with potential applications in various industries. Its reactivity and structural diversity make it an attractive candidate for further exploration and development.
Used in the Synthesis of 6-Methyl-3-nitro-2-(2-phenylhydrazinyl)pyridine (MNPHP):
2-Fluoro-6-methyl-3-nitropyridine is used as a key reactant in the synthesis of MNPHP, a compound with potential applications in the pharmaceutical industry. The synthesis of MNPHP from 2-fluoro-6-methyl-3-nitropyridine demonstrates its utility as a versatile intermediate in the development of new chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 19346-45-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,3,4 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 19346-45:
(7*1)+(6*9)+(5*3)+(4*4)+(3*6)+(2*4)+(1*5)=123
123 % 10 = 3
So 19346-45-3 is a valid CAS Registry Number.
19346-45-3Relevant articles and documents
Synthesis and physicochemical properties of the methyl-nitro-pyridine-disulfide: X-ray, NMR, electron absorption and emission, IR and Raman studies and quantum chemical calculations
Bryndal, Iwona,Hanuza, Jerzy,Lis, Tadeusz,S?siadek, Wojciech,Wandas, Maria
, (2022/03/14)
The methyl-nitro-pyridine-disulfide derivative [2,2′-disulfanodiylbis(6-metyl-3-nitropyridine)] was synthesized and characterized by means of structural and spectroscopic measurements. On the basis of X-ray diffraction studies, it was found that the studied compound crystallizes in the centrosymmetric monoclinic space group P21/n (Z = 2). The disulfide C-S-S-C bridge links two identical fragments formed by pyridine rings substituted with methyl and nitro groups. Such a structure was confirmed by 1H and 13C NMR studies as well as IR, Raman, UV–VIS and emission spectra. Quantum chemical DFT calculations were applied in the analysis of the obtained results. The vibrational characteristics were reported and dynamical properties of this moiety were discussed. A full set of the normal modes characteristic for the disulfide bridge was identified and assigned to the respective IR and Raman bands. The results of structural and spectroscopic studies were used to find the dependence between the conformation of the ?-S-S-? system and its optic properties. The experimental electron and emission spectra were analyzed in terms of the calculated singlet and triplet states that allowed assigning the unique spectral pattern originating from the electrons of the C-S-S-C bridge system.
