193476-02-7

Basic information

• Product Name: (+)-(2R)-2-[bis(phenylmethyl)amino]-2-phenylethanol
• Synonyms: (+)-(2R)-2-[bis(phenylmethyl)amino]-2-phenylethanol
• CAS NO: 193476-02-7
• Molecular Weight: 317.431
• Mol File: 193476-02-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (+)-(2R)-2-[bis(phenylmethyl)amino]-2-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(2R)-2-[bis(phenylmethyl)amino]-2-phenylethanol(193476-02-7)
• EPA Substance Registry System: (+)-(2R)-2-[bis(phenylmethyl)amino]-2-phenylethanol(193476-02-7)

Safety Data

• Hazardous Substances Data: 193476-02-7(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 100-46-9 benzylamine 
• 100-44-7 benzyl chloride 
• 103-49-1 dibenzylamine 
• 87802-71-9 (E)-methyl cinnamyl carbonate 
• 174023-92-8 D-dibenzylaminophenylglycinal 
• 875-74-1 (R)-phenylglycine 
• 1355025-46-5 (R)-α-(dibenzylamino)phenylacetic acid (S)-1,2-bis(isopropoxycarbonyl)ethyl ester 
• 1224386-98-4 (2-methoxy-2-oxo-(S)-1-phenylethyl) (R)-α-dibenzylaminophenylacetate 
• 100-39-0 benzyl bromide 

Downstream Products

• 249923-18-0 (1R,2S)-1-Dibenzylamino-1-phenyl-propan-2-ol 
• 249923-04-4 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (1S,2R)-2-dibenzylamino-1-methyl-2-phenyl-ethyl ester 
• 180067-82-7 (1R,2R)-1-Dibenzylamino-1-phenyl-butan-2-ol 
• 180067-87-2 (1R,2R)-1-amino-1-phenyl-2-butanol 
• 103-49-1 dibenzylamine 
• 267884-82-2 (1S,4S)-N,N-(dibenzyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 
• 267884-77-5 (1S,R,4S)-N,N-(dibenzyl)-4-amino-1-(3,4-dichlorophenyl)-4-phenyl-1-butanol 
• 267884-84-4 cis-(1S,4S)-N-(tert-butoxycarbonyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 
• 267884-85-5 cis-(1S,4S)-N-(tert-butoxycarbonyl)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 
• 267884-79-7 (4S)-ethyl-4-N,N-(dibenzyl)-4-amino-4-phenyl-(E)-2-butenoate 
• 267884-80-0 (4S)-methyl-N,N-(dibenzyl)-4-amino-4-phenylbutanoate 

Relevant articles and documents

Iridium-catalyzed asymmetric allylic substitutions with bulky amines/oxidative double bond cleavage - Entry into the reetz synthesis of amino alcohols

Branched allylic amines were prepared by Ir-catalyzed enantioselective allylic aminations with the bulky N-nucleophiles HN(Boc)2 and HNBn2. The products were transformed into N-protected amino aldehydes, which were either reduced or coupled diastereoselectively with organometallic compounds to give vicinal amino alcohols. A formal synthesis of the neurokinin receptor antagonist (+)-L-733060 was carried out as an application. Ir-catalyzed enantioselective allylic aminations with bulky N-nucleophiles HN(Boc)2 and HNBn2 gave N-protected allylic amines, which were transformed into N-protected chiral amino aldehydes. These are useful chiral building blocks as previously demonstrated by Reetz et al. A formal synthesis of the neurokinin receptor antagonist (+)-L-733060 was carried out as an application.

L-tartaric acid as a new chiral auxiliary for asymmetric synthesis of piperazinones, morpholinones, dihydroquinoxalinones and dihydrobenzoxazinones

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Asymmetric synthesis of 3-Substituted morpholinones and piperazinones by L-Malate-mediated dynamic kinetic resolution of a-bromo esters

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