193481-78-6Relevant articles and documents
A deuterated benzimidazole compound of preparation method and use thereof
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Paragraph 0041-0045, (2019/07/04)
The invention discloses a formula (I) indicated by the deuterium generation of benzene and imidazole compound or its pharmaceutically acceptable salt preparation method and use. The invention the deuterium generation of benzene and imidazole compound can
BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS
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Page/Page column 99-100, (2010/04/03)
Provided herein are sirtuin-modulating compounds of formula (II) The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
ORGANIC COMPOUNDS
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Page/Page column 26, (2008/06/13)
Compounds of formula (I) in free or salt form, where Y, R1, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by the CXCR2 receptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.