193549-97-2

Basic information

• Product Name: 1-(5-tert-Butyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester
• Synonyms: 1-(5-tert-Butyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester
• CAS NO: 193549-97-2
• Molecular Weight: 263.299
• Mol File: 193549-97-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(5-tert-Butyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-tert-Butyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester(193549-97-2)
• EPA Substance Registry System: 1-(5-tert-Butyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester(193549-97-2)

Safety Data

• Hazardous Substances Data: 193549-97-2(Hazardous Substances Data)

Upstream product

• 14762-48-2 ethyl 2-diazo-3-oxo-propanoate 
• 82560-12-1 3-tert-butyl-1H-pyrazole-5-amine 

Relevant articles and documents

Preparation and pyrolysis of 1-(pyrazol-5-yl)-1,2,3-triazoles and related compounds

1-(Pyrazol-5-yl)-1,2,3-triazoles 8a, 9a and 10 are prepared by cycloaddition of 5-azidopyrazoles with methyl prop-2-ynoate. The regiochemistry of the process is confirmed by synthesis of 9a using an authentic route from ethyl 2-formyl-2-diazoacetate 13. Flash vacuum pyrolysis of 8a, 9a and 10 gives 5-methoxypyrazolo[1,5-a]pyrimidin-7-ones 16-18 by a mechanism involving an unexpected oxoketenimineimidoyl ketene rearrangement as the key step. The mechanism is supported by a 13C labelling experiment. A general route to pyrazolo[1,5-a]pyrimidin-7-ones from pyrazolylaminomethylene Meldrum's acid derivatives (e.g. 30-32) is also reported.