19368-10-6

Basic information

• Product Name: 2-[[(4-CARBOXYPHENYL)AMINO]CARBONYL]-BENZOIC ACID
• Synonyms: 2-[[(4-CARBOXYPHENYL)AMINO]CARBONYL]-BENZOIC ACID
• CAS NO: 19368-10-6
• Molecular Formula: C₁₅H₁₁NO₅
• Molecular Weight: 285.25
• Mol File: 19368-10-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[[(4-CARBOXYPHENYL)AMINO]CARBONYL]-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[[(4-CARBOXYPHENYL)AMINO]CARBONYL]-BENZOIC ACID(19368-10-6)
• EPA Substance Registry System: 2-[[(4-CARBOXYPHENYL)AMINO]CARBONYL]-BENZOIC ACID(19368-10-6)

Safety Data

• Hazardous Substances Data: 19368-10-6(Hazardous Substances Data)

Usage

Derivative

Anthranilic acid and benzoic acid

Usage

Pharmaceutical industry (building block for drug synthesis)

Applications

Anti-inflammatory, analgesic, and antipyretic drugs; dyes and pigments production; research and development of new chemical entities

Potential uses

Polymer and organic compound manufacturing

Functional groups

Carboxyl (-COOH), amino (-NH2), carbonyl (-C=O)

Structural properties

Two benzene rings connected by an amide bond, with additional carboxyl group on one of the benzene rings.

Upstream product

• 85-44-9 phthalic anhydride 
• 3939-41-1 4-(benzylideneimino)benzoic acid 
• 2142-03-2 2-p-tolylisoindoline-1,3-dione 
• 150-13-0 4-amino-benzoic acid 
• 106-49-0 p-toluidine 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Downstream Products

• 5383-83-5 4–(1,3-dioxoisoindolin-2-yl)benzoyl chloride 
• 5383-82-4 4-phthalimidobenzoic acid 
• 1548329-48-1 [(n-Bu₂Sn)₂(4-carboxyphenylcarbamoyl)benzoate]₂*toluene 

Relevant articles and documents

Compounds and methods for inducing chondrogenesis

The present invention provides compounds and compositions for the amelioration of arthritis and joint injuries by inducing mesenchymal stem cells into chondrocytes.

Functionalised acyl ferrocenes: Crystal and molecular structures of 4-aminobenzoylferrocene, 4-hydroxybenzoylferrocene and 1,1′-bis(4-hydroxybenzoyl)ferrocene

Improved methods of synthesis are reported for FcCOC6H4F-4 1a, FcCOC6H4OMe-4 1b and Fcd(COC6H4OMe-4)2 2b [Fc = (C5H5)Fe(C5H4); Fcd = (C5H4)Fe(C5H4)]: demethylation of 1b and 2b, using AlCl3 in 1,1,2-trichloroethane, yields FcCOC6H4OH 1f and Fcd(COC6H4OH)2 2f respectively. Acylation of ferrocene using 4-phthalimidobenzoyl chloride yields 4-(phthalimidobenzoyl)ferrocene 1c, hydrazinolysis of which yields FcCOC6H4NH2-4 1d. Crystal structures are reported for 1d, 1f and 2f: in 1d and 1f the molecules are linked into spiral chains by means of N-H ... O=C and O-H ... O=C hydrogen bonds respectively; in 2f the O-H ... O=C hydrogen bonds link the centrosymmetric molecules into continuous two-dimensional nets, two independent sets of which are interwoven.