193821-69-1Relevant articles and documents
87. Synthesis and Evaluation of 2-{[(2-Oxo-1H-quinolin-8-yl)oxy]methyl}-Substituted α-Methylidene-γ-butyrolactones
Tzeng, Cherng-Chyi,Chen, Yeh-Long,Wang, Chyi-Jia,Wang, Tai-Chi,Chang, Ya-Ling,Teng, Che-Ming
, p. 1161 - 1168 (1997)
O-Alkylation of 8-hydroxy-1H-quinolin-2-one (1) afforded 8-(2-oxopropoxy)-1H-quinolin-2-one (2) which was immediately cyclized to form the tricyclic 2,3-dihydro-3-hydroxy-3-methyl-5H-pyrido[1,2,3-de][1,4]benzoxazine-5-one (3). The Reformatsky-type condens