19390-75-1

Basic information

• Product Name: methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate
• Synonyms: methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate
• CAS NO: 19390-75-1
• Molecular Weight: 174.077
• Mol File: 19390-75-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate(19390-75-1)
• EPA Substance Registry System: methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate(19390-75-1)

Safety Data

• Hazardous Substances Data: 19390-75-1(Hazardous Substances Data)

Upstream product

• 10186-63-7 2-fluoro-2-methoxy trifluoropropanoic acid methyl ester 

Relevant articles and documents

Methyl 3,3,3-trifluoropyruvate: An improved procedure starting from hexafluoropropene-1,2-oxide; identification of byproducts

Optimized laboratory-scale preparation of methyl 3,3,3-trifluoropyruvate (3, MTFP) has been developed starting from industrial hexafluoropropene-1,2-oxide (1, HFPO) via methyl 2,3,3,3-tetrafluoro-2-methoxypropanoate (2, MTPr), which was transformed to 3 using sulfuric acid with isolated yields up to 81%. Byproducts formed in the transformation of 2 to 3, viz. methyl trifluoroacetate (4, MTAc), methyl 3,3,3-trifluoropyruvate hydrate (5), methyl hemiacetal of trifluoropyruvate (6), a dimer of methyl 3,3,3-trifluoropyruvate hydrate (7, DimMTP), and methyl fluorosulfate (8, Sulf) were identified and their amounts determined under various experimental conditions. Potential reaction pathways leading to the formation of the byproducts are discussed.