19396-73-7

Basic information

• Product Name: 1-PHENYL-1-OCTANOL
• Synonyms: AURORA KA-6951;1-PHENYL-1-OCTANOL;(R,S)-1-Phenyl-octan-1-ol;1-Phenyloctyl alcohol
• CAS NO: 19396-73-7
• Molecular Formula: C₁₄H₂₂O
• Molecular Weight: 206.32
• Mol File: 19396-73-7.mol
• Article Data: 58

Chemical Properties

• Boiling Point: 285.1 °C at 760 mmHg
• Flash Point: 131 °C
• Appearance: /
• Density: 0.939
• CAS DataBase Reference: 1-PHENYL-1-OCTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-1-OCTANOL(19396-73-7)
• EPA Substance Registry System: 1-PHENYL-1-OCTANOL(19396-73-7)

Safety Data

• Hazardous Substances Data: 19396-73-7(Hazardous Substances Data)

Usage

General Description

1-PHENYL-1-OCTANOL, also known as octylphenol, is a chemical compound with the molecular formula C14H22O. It is a colorless to pale yellow liquid with a faint floral odor, and is insoluble in water but soluble in most organic solvents. This chemical is primarily used as an intermediate in the manufacturing of various chemicals and products, such as antioxidants, plasticizers, and surfactants. It is also used as a fragrance ingredient in perfumes and cosmetics. However, 1-PHENYL-1-OCTANOL has been identified as an endocrine disruptor, with potential negative effects on human health and the environment, leading to increased concerns and regulations regarding its use.

Upstream product

• 124-13-0 Octanal 
• 629-04-9 1-Bromoheptane 
• 100-52-7 benzaldehyde 
• 86766-12-3 (3S,5S)-3-Heptyl-3-methyl-5-phenyl-[1,2]dioxolane 
• 98-87-3 benzylidene dichloride 
• 3244-73-3 tri-n-heptylborane 
• 76376-91-5 n-heptyl phenyl selenide 
• 591-50-4 iodobenzene 
• 20780-53-4 (R)-Styrene oxide 
• 3761-92-0 n-hexylmagnesium bromide 
• 24767-82-6 1-heptyl 4-methylbenzenesulfonate 
• 934-56-5 trimethyl(phenyl)stannane 
• 98-86-2 acetophenone 
• 111-27-3 hexan-1-ol 

Downstream Products

• 98934-93-1 2-{2-[1-(1-Phenyl-octyloxy)-ethoxy]-ethoxymethyl}-oxirane 
• 28665-60-3 (E)-1-phenyl-1-octene 
• 1674-37-9 n-octanophenone 
• 104513-01-1 N-(1-phenyl-octyl)-acetamide 
• 123824-37-3 (α-acetoxyoctyl)benzene 
• 1250260-52-6 C₁₆H₂₁F₃O₂ 
• 131320-88-2 (S)-(-)-1-phenyl-1-octanol acetate 
• 17222-56-9 1,1-diphenyloctan-1-ol 
• 78605-96-6 jasminaldehyde 

Relevant articles and documents

Ultrasound in Organic Synthesis. 13. Some Fundamental Aspects of the Sonochemical Barbier Reaction

The Barbier reaction of benzaldehyde, n-heptyl bromide, and lithium was effected under various sonochemical conditions.The rate of formation of 1-phenyloctanol depends strongly on the intensity of the ultrasonic waves and the temperature.For both parameters, an optimum is observed.An unusual variation of rate with temperature is evidenced, which reveals that the reaction is not mass-transport controlled.Electron microscopy examination of the metal shows the very important activation role of the acoustic waves, through the cavitation phenomenon.

Homoleptic cobalt(II) phenoxyimine complexes for hydrosilylation of aldehydes and ketones without base activation of cobalt(II)

Air-stable, easy to prepare, homoleptic cobalt(II) complexes bearing pendant-modified phenoxyimine ligands were synthesized and determined. The complexes exhibited high catalytic performance for reducing aldehydes and ketones via catalytic hydrosilylation, where a hydrosilane and a catalytic amount of the cobalt(II) complex were added under base-free conditions. The reaction proceeded even in the presence of excess water, and excellent functional-group tolerance was observed. Subsequent hydrolysis gave the alcohol in high yields. Moreover, H2O had a critical role in activation of the Co(II) catalyst with hydrosilane. Several additional results also indicated that the cobalt(II) center acts as an active catalyst in the hydrosilylation of aldehydes and ketones.

Selective C-alkylation Between Alcohols Catalyzed by N-Heterocyclic Carbene Molybdenum

The first implementation of a molybdenum complex with an easily accessible bis-N-heterocyclic carbene ligand to catalyze β-alkylation of secondary alcohols via borrowing-hydrogen (BH) strategy using alcohols as alkylating agents is reported. Remarkably high activity, excellent selectivity, and broad substrate scope compatibility with advantages of catalyst usage low to 0.5 mol%, a catalytic amount of NaOH as the base, and H2O as the by-product are demonstrated in this green and step-economical protocol. Mechanistic studies indicate a plausible outer-sphere mechanism in which the alcohol dehydrogenation is the rate-determining step.