193967-73-6

Basic information

• Product Name: Propanedioic acid, methylphenyl-, bis(3-nitrophenyl) ester
• CAS NO: 193967-73-6
• Molecular Formula: C22H16N2O8
• Molecular Weight: 436.378
• Mol File: 193967-73-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, methylphenyl-, bis(3-nitrophenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, methylphenyl-, bis(3-nitrophenyl) ester(193967-73-6)
• EPA Substance Registry System: Propanedioic acid, methylphenyl-, bis(3-nitrophenyl) ester(193967-73-6)

Safety Data

• Hazardous Substances Data: 193967-73-6(Hazardous Substances Data)

Upstream product

• 554-84-7 meta-nitrophenol 
• 150080-50-5 methyl-phenyl-malonyl chloride 
• 83-13-6 diethyl 2-phenylmalonate 
• 4371-02-2 2-methyl-2-phenylmalonic acid 

Relevant articles and documents

Reactions of amino-substituted cyclodextrins with 2-arylpropanoic acid derivatives

Reactions of 6A-amino-6A-deoxy-β-cyclodextrin and 3A-amino-3A-deoxy-(2AS,3 AS)-β-cyclodextrin with the 3-nitrophenyl esters of 2-phenylpropanoic acid and Ibuprofen occur with only low diastereoselectivity, to afford the corresponding arylpropanamido-substituted cyclodextrins. These amides are also formed by decarboxylation of corresponding malonates, again with only low diastereoselectivity. The n.m.r. spectra of the amido-substituted cyclodextrins indicate that the aryl substituent is included within the cyclodextrin annulus at low temperature, but becomes dissociated from the cavity as the temperature is increased.