19407-45-5

Basic information

• Product Name: 2-Benzamido-5-chlorobenzoic acid
• Synonyms: 2-Benzamido-5-chlorobenzoic acid
• CAS NO: 19407-45-5
• Molecular Formula: C₁₄H₁₀ClNO₃
• Molecular Weight: 275.6871
• EINECS: 922-761-6
• Product Categories: Acids & Esters;Anilines, Amides & Amines;Chlorine Compounds
• Mol File: 19407-45-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-Benzamido-5-chlorobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzamido-5-chlorobenzoic acid(19407-45-5)
• EPA Substance Registry System: 2-Benzamido-5-chlorobenzoic acid(19407-45-5)

Safety Data

• Hazardous Substances Data: 19407-45-5(Hazardous Substances Data)

Usage

General Description

2-Benzamido-5-chlorobenzoic acid is a chemical compound with the molecular formula C14H10ClNO3. It is a derivative of benzoic acid, containing both an amide and a chloro group in its structure. 2-Benzamido-5-chlorobenzoic acid is commonly used in organic synthesis and pharmaceutical research due to its potential bioactive properties. Its structure makes it a potential candidate for the development of new drugs, particularly for the treatment of various diseases. Additionally, it has been used as a building block for the preparation of other complex organic molecules, making it an important chemical in the field of medicinal chemistry.

InChI:InChI=1S/C14H10ClNO3/c15-10-6-7-12(11(8-10)14(18)19)16-13(17)9-4-2-1-3-5-9/h1-8H,(H,16,17)(H,18,19)

Upstream product

• 67-56-1 methanol 
• 112182-50-0 6-chloro-2-phenylquinolin-4(1H)-one 
• 98-88-4 benzoyl chloride 
• 635-21-2 5-chloroanthranilic acid 
• 23746-76-1 5-chloro-2-phenylindole 

Downstream Products

• 1348979-36-1 6-chloro-3-(3-chloro-4-fluorophenyl)-2-phenylquinazolin-4(3H)-one 
• 1348979-38-3 C₂₁H₁₄ClFN₂O 
• 1348979-39-4 C₂₁H₁₄Cl₂N₂O 
• 1348979-41-8 6-chloro-3-(4-fluorophenyl)-2-phenylquinazolin-4(3H)-one 
• 1348979-42-9 6-chloro-3-(3-chlorophenyl)-2-phenylquinazolin-4(3H)-one 
• 7079-14-3 6-chloro-3-(4-methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one 
• 687639-17-4 6-chloro-3-(4-chlorophenyl)-2-phenylquinazolin-4(3H)-one 
• 7033-51-4 6-chloro-2-phenyl-benzo[d][1,3]oxazin-4-one 

Relevant articles and documents

From Methaqualone and Beyond: Structure - Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA

Methaqualone (2-methyl-3-(o-tolyl)-quinazolin-4(3H)-one, MTQ) is a moderately potent positive allosteric modulator (PAM) of GABAA receptors (GABAARs). In a previous structure-activity relationship (SAR) study probing the importance of 2- and 3-substituent

Nucleophilic ring-opening of benzoxazinones by DBU: Some observations

This communication demonstrates the formation of an unusual nucleophilic ring opening of benzoxazinones by 1,8-diazabicycloundec-7-ene (DBU). This observation contradicts the intrinsic feature of a hindered nonnucleophilic base like DBU. Confirmation of t

Production of 3-Benzoyl-2,1-benzisoxazoles, 2-Phenyl-4H-3,1-benzoxazin-4-ones, and Novel Quinolinone Derivatives from 2-Phenylquinolin-4(1H)-ones and Sodium Dichloroisocyanurate

A simple synthesis of certain 3-benzoyl-2,1-benzisoxazoles 6 is accomplished via treatment of the corresponding 2-phenylquinolin-4(1H)-one 1 with sodium dichloroisocyanurate 2 in methanolic aq. alkali; the isomeric 2-phenyl-4H-3,1-benzoxazin-4-one 7 is al