19419-23-9

Basic information

• Product Name: 1,3-Cyclohexanedione,2,2'-(phenylmethylene)bis[5,5-dimethyl-
• Synonyms: 1,3-Cyclohexanedione,2,2'-benzylidenebis[5,5-dimethyl- (6CI,8CI); NSC 406331
• CAS NO: 19419-23-9
• Molecular Formula: C23H28 O4
• Molecular Weight: 368.473
• Mol File: 19419-23-9.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1,3-Cyclohexanedione,2,2'-(phenylmethylene)bis[5,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Cyclohexanedione,2,2'-(phenylmethylene)bis[5,5-dimethyl-(19419-23-9)
• EPA Substance Registry System: 1,3-Cyclohexanedione,2,2'-(phenylmethylene)bis[5,5-dimethyl-(19419-23-9)

Safety Data

• Hazardous Substances Data: 19419-23-9(Hazardous Substances Data)

Usage

General Description

1,3-Cyclohexanedione,2,2'-(phenylmethylene)bis[5,5-dimethyl- is a chemical compound with a complex molecular structure. It consists of a cyclohexanedione ring with two methyl groups attached to the 5th position, and a phenylmethylene group bridging the 2,2' positions. 1,3-Cyclohexanedione,2,2'-(phenylmethylene)bis[5,5-dimethyl- is commonly used in organic synthesis and as a building block for the preparation of various derivatives. It is known for its ability to undergo condensation reactions and form complex cyclic structures. This chemical is of interest to researchers and chemists for its potential applications in pharmaceuticals, materials science, and organic chemistry.

Upstream product

• 100-52-7 benzaldehyde 
• 126-81-8 dimedone 
• 110-89-4 piperidine 
• 64-17-5 ethanol 
• 5381-33-9 2-benzylidene-indan-1,3-dione 
• 1137-96-8 N-(benzylidene)aniline N-oxide 
• 562-13-0 2,2-dimethyl-1,3-cyclohexanedione 
• 620-80-4 ethyl 2-benzylidene acetoacetate 
• 17572-39-3 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenylcyclohexanone 

Downstream Products

• 824428-86-6 2,2''-benzylidene-bis-[1,2']biindenylidene-3,1',3'-trione 
• 19744-83-3 3,3,6,6-tetramethyl-9-phenyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8-(2H)-dione 
• 2769-21-3 3,3,6,6-tetramethyl-9-phenyl-3,4,6,7,9,10-hexahydro-2H,5H-acridine-1,8-dione 
• 141076-60-0 10-(4-chlorophenyl)-3,3,6,6-tetramethyl-9-phenyl-3,4,6,7,9,10-hexahydroacridine-1,8-(2H,5H)-dione 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Diastereoselective and Reversed Regioselective Annulations of N-Alkyl Anilines to Julolidines and Lilolidines

A three-component annulation reaction of N-alkyl anilines, cyclic 1,3-dicarbonyl compounds, and aryl aldehydes to julolidines and lilolidines is reported. The 6π-electrocyclization enabled the annulation to proceed with reversed regioselectivity as compar

Rapid Chemical Reaction Monitoring by Digital Microfluidics-NMR: Proof of Principle Towards an Automated Synthetic Discovery Platform

Microcoil nuclear magnetic resonance (NMR) has been interfaced with digital microfluidics (DMF) and is applied to monitor organic reactions in organic solvents as a proof of concept. DMF permits droplets to be moved and mixed inside the NMR spectrometer t

Tetraketones: A new class of tyrosinase inhibitors

Twenty-eight tetraketones (1-28) with variable substituents at C-7 were synthesized and evaluated as tyrosinase inhibitors. Remarkably compounds 25 (IC50 = 2.06 μM), 11 (IC50 = 2.09 μM), 15 (IC 50 = 2.61 μM), and 27 (ICsu

Merging supramolecular catalysis and aminocatalysis: Amino-appended β-cyclodextrins (ACDs) as efficient and recyclable supramolecular catalysts for the synthesis of tetraketones

Well-designed amino-appended β-cyclodextrins (ACDs) with an amino side chain of different lengths at the primary face of β-CD were synthesized and employed in the catalytic synthesis of a series of tetraketones as supramolecular catalysts in water for the first time. Yields of 58-97% were obtained with up to 30 examples of substrate. The catalyst could be recycled easily, while a 92% yield and 84% rate of catalyst recovery could be achieved after 8 cycles of catalyst recycling. Moreover, a catalytic mechanism merging supramolecular catalysis and aminocatalysis could be proposed through detailed 1D and 2D NMR, ESI-MS and Job plot analyses. This protocol retained the promising characteristics of ambient temperature, green medium, simple operation, broad substrate scope, excellent yields, superb catalyst recycling performance and unique catalytic mechanism.